U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MIER1 MIER1 transcriptional regulator [ Homo sapiens (human) ]

Gene ID: 57708, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
MIER1provided by HGNC
Official Full Name
MIER1 transcriptional regulatorprovided by HGNC
Primary source
HGNC:HGNC:29657
See related
Ensembl:ENSG00000198160 MIM:616848; AllianceGenome:HGNC:29657
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ER1; MI-ER1
Summary
This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]
Expression
Ubiquitous expression in bone marrow (RPKM 19.6), colon (RPKM 10.3) and 24 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MIER1 in Genome Data Viewer
Location:
1p31.3
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (66924990..66988619)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (66802518..66866111)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (67390673..67454302)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene insulin like 5 Neighboring gene dynein axonemal intermediate chain 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1167 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 973 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1168 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 974 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 975 Neighboring gene MPRA-validated peak274 silencer Neighboring gene MPRA-validated peak275 silencer Neighboring gene solute carrier family 35 member D1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 976 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:67486227-67487025 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 977 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 978 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:67562817-67563435 Neighboring gene small nucleolar RNA SNORA31 Neighboring gene chromosome 1 open reading frame 141 Neighboring gene NANOG hESC enhancer GRCh37_chr1:67602886-67603396 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1169 Neighboring gene interleukin 23 receptor Neighboring gene RNA, U6 small nuclear 586, pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A potential histone-chaperone activity for the MIER1 histone deacetylase complex. Wang S, et al. Nucleic Acids Res, 2023 Jul 7. PMID 37099381, Free PMC Article
  2. Molecular cloning of human er1 cDNA and its differential expression in breast tumours and tumour-derived cell lines. Paterno GD, et al. Gene, 1998 Nov 5. PMID 9813250
  3. Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization. Paterno GD, et al. Gene, 2002 Jul 24. PMID 12242014
  4. Changes in subcellular localisation of MI-ER1 alpha, a novel oestrogen receptor-alpha interacting protein, is associated with breast cancer progression. McCarthy PL, et al. Br J Cancer, 2008 Aug 19. PMID 18665173, Free PMC Article
  5. Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells. Clements JA, et al. PLoS One, 2012. PMID 22384264, Free PMC Article

See all (55) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A potential histone-chaperone activity for the MIER1 histone deacetylase complex.
    Title: A potential histone-chaperone activity for the MIER1 histone deacetylase complex.
  2. Histone deacetylase assays confirmed that MIER2, but not MIER3 complexes, have associated deacetylase activity.
    Title: Differential HDAC1 and 2 Recruitment by Members of the MIER Family.
  3. Biochemical analysis of the BAHD1-associated multiprotein complex identifies MIER proteins as novel partners of BAHD1 and suggests that BAHD1-MIER interaction forms a hub for histone deacetylases and methyltransferases
    Title: Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.
  4. Insulin and IGF-1 alter the subcellular localization of MIER1alpha in breast carcinoma cells.
    Title: Insulin and IGF-1, but not 17β-estradiol, alter the subcellular localization of MIER1α in MCF7 breast carcinoma cells.
  5. nuclear targeting of MIER1alpha requires an intact ELM2 domain and is dependent on interaction with HDAC1/2
    Title: Nuclear localization of the transcriptional regulator MIER1α requires interaction with HDAC1/2 in breast cancer cells.
  6. the first immunohistochemical study of the MIER1alpha protein expression pattern in human tissues, is reported.
    Title: Protein expression pattern of human MIER1 alpha, a novel estrogen receptor binding protein.
  7. Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells
    Title: Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells.
  8. Loss of nuclear MI-ER1 alpha might contribute to the development of invasive breast carcinoma
    Title: Changes in subcellular localisation of MI-ER1 alpha, a novel oestrogen receptor-alpha interacting protein, is associated with breast cancer progression.
  9. we investigated the role of hMI-ER1alpha and hMI-ER1beta in the regulation of transcription.We demonstrate that this repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
    Title: Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain.
  10. the association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters
    Title: The SANT domain of human MI-ER1 interacts with Sp1 to interfere with GC box recognition and repress transcription from its own promoter.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • KIAA1610, MGC131940, MGC150640, MGC150641, DKFZp781G0451

Gene Ontology Provided by GOA

Function Evidence Code Pubs
contributes_to histone deacetylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone deacetylase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of canonical NF-kappaB signal transduction HMP PubMed 
involved_in regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription repressor complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
mesoderm induction early response protein 1
Names
mesoderm induction early response 1 homolog
mesoderm induction early response 1, transcriptional regulator

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029847.1 RefSeqGene

    Range
    5096..68725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001077700.3 → NP_001071168.2  mesoderm induction early response protein 1 isoform b

    See identical proteins and their annotated locations for NP_001071168.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region and uses an alternate upstream translation start site, compared to variant 1. The resulting isoform (b) has a longer and distinct N-terminus, compared to isoform a.
    Source sequence(s)
    AK302061, AL500525, BM987758
    Consensus CDS
    CCDS53326.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000383820.1, ENST00000401041.6
    Conserved Domains (2) summary
    cd11661
    Location:341 → 385
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:235 → 284
    ELM2; ELM2 domain

  2. NM_001077701.3 → NP_001071169.1  mesoderm induction early response protein 1 isoform c

    See identical proteins and their annotated locations for NP_001071169.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The resulting isoform (c, also known as N3-beta) has a shorter and distinct N-terminus, compared to isoform a.
    Source sequence(s)
    AF515446, AL500525, BM987758
    Consensus CDS
    CCDS41348.1
    UniProtKB/Swiss-Prot
    C9JFD4, Q08AE0, Q32NC4, Q5T104, Q5TAD1, Q5TAD2, Q5TAD4, Q5TAD5, Q6AHY8, Q86TB4, Q8N108, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2
    Related
    ENSP00000347514.3, ENST00000355356.3
    Conserved Domains (2) summary
    cd11661
    Location:288 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:182 → 231
    ELM2; ELM2 domain

  3. NM_001077702.3 → NP_001071170.2  mesoderm induction early response protein 1 isoform d

    See identical proteins and their annotated locations for NP_001071170.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (d) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AF515448, AK302061, AL500525, BM987758
    Consensus CDS
    CCDS53327.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000360055.1, ENST00000371016.5
    Conserved Domains (2) summary
    cd11661
    Location:305 → 349
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:199 → 248
    ELM2; ELM2 domain

  4. NM_001077703.3 → NP_001071171.2  mesoderm induction early response protein 1 isoform e

    See identical proteins and their annotated locations for NP_001071171.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks an alternate exon in the 5' coding region, uses an alternate upstream translation start site, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (e) has a longer and distinct N-terminus and a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AK302061, AL500525, AY124187, BM987758
    Consensus CDS
    CCDS53325.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000360053.1, ENST00000371014.5
    Conserved Domains (2) summary
    cd11661
    Location:341 → 385
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:235 → 284
    ELM2; ELM2 domain

  5. NM_001077704.3 → NP_001071172.1  mesoderm induction early response protein 1 isoform f

    See identical proteins and their annotated locations for NP_001071172.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at an alternate start codon, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (f, also known as N3-alpha), has shorter and distinct N- and C-termini, compared to isoform a.
    Source sequence(s)
    AL500525, AY124188, BM987758
    Consensus CDS
    CCDS41347.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000383821.3, ENST00000401042.7
    Conserved Domains (2) summary
    cd11661
    Location:288 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:182 → 231
    ELM2; ELM2 domain

  6. NM_001146110.2 → NP_001139582.1  mesoderm induction early response protein 1 isoform a

    See identical proteins and their annotated locations for NP_001139582.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) uses an alternate splice site in the 5' UTR compared to variant 1. Both variants 1 and 10 encode the same isoform (a).
    Source sequence(s)
    AK302061, AK307717, AL500525, BC108726, BM987758
    Consensus CDS
    CCDS53329.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000350321.2, ENST00000357692.6
    Conserved Domains (2) summary
    cd11661
    Location:305 → 349
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:199 → 248
    ELM2; ELM2 domain

  7. NM_001146111.2 → NP_001139583.1  mesoderm induction early response protein 1 isoform g

    See identical proteins and their annotated locations for NP_001139583.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (g) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AK302061, AL500525, BC108726, BM987758
    Consensus CDS
    CCDS53328.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000360057.3, ENST00000371018.7
    Conserved Domains (2) summary
    cd11661
    Location:305 → 349
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:199 → 248
    ELM2; ELM2 domain

  8. NM_001146112.2 → NP_001139584.1  mesoderm induction early response protein 1 isoform h

    See identical proteins and their annotated locations for NP_001139584.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks a portion of the 5' coding region and initiates translation at a downstream in-frame start codon, compared to variant 1. The resulting isoform (h) has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AF515446, AK302061, AL139216, AL500525, BM987758
    UniProtKB/Swiss-Prot
    Q8N108
    Conserved Domains (2) summary
    cd11661
    Location:261 → 305
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:155 → 204
    ELM2; ELM2 domain

  9. NM_001146113.2 → NP_001139585.1  mesoderm induction early response protein 1 isoform i

    See identical proteins and their annotated locations for NP_001139585.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) lacks two alternate exons in the 5' coding region, initiates translation at a downsteram in-frame start codon, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (i) has a shorter N-terminus and a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AK302061, AL500525, BC125217, BM987758
    Consensus CDS
    CCDS53330.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000348253.6, ENST00000355977.10
    Conserved Domains (2) summary
    cd11661
    Location:225 → 269
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:119 → 168
    ELM2; ELM2 domain

  10. NM_001278215.2 → NP_001265144.1  mesoderm induction early response protein 1 isoform j

    See identical proteins and their annotated locations for NP_001265144.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) lacks multiple 3' exons and its transcription extends past a splice site used in variant 1, resulting in a distinct 3' coding region and 3' UTR. The encoded isoform (j) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AL139216, BC066898
    Consensus CDS
    CCDS60163.1
    UniProtKB/Swiss-Prot
    Q8N108
    Related
    ENSP00000360051.2, ENST00000371012.6

  11. NM_001350530.2 → NP_001337459.1  mesoderm induction early response protein 1 isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) contains an alternate exon in its 5' coding region, resulting in a shorter 5' UTR and the use of an alternate upstream translation start site, compared to variant 1. The resulting isoform (k) has a longer and distinct N-terminus, compared to isoform a
    Source sequence(s)
    AF515448, AK302061, AL139216, AL500525, BM987758, CB998535
    Conserved Domains (2) summary
    cd11661
    Location:378 → 422
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:272 → 321
    ELM2; ELM2 domain

  12. NM_020948.4 → NP_065999.2  mesoderm induction early response protein 1 isoform a

    See identical proteins and their annotated locations for NP_065999.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform a. Both variants 1 and 10 encode the same isoform (a).
    Source sequence(s)
    AF515448, AK302061, AL500525, BM987758
    Consensus CDS
    CCDS53329.1
    UniProtKB/Swiss-Prot
    Q8N108
    Conserved Domains (2) summary
    cd11661
    Location:305 → 349
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:199 → 248
    ELM2; ELM2 domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    66924990..66988619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001923.2 → XP_016857412.1  mesoderm induction early response protein 1 isoform X4

  2. XM_011541865.3 → XP_011540167.1  mesoderm induction early response protein 1 isoform X1

    Conserved Domains (3) summary
    smart00717
    Location:365 → 410
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:365 → 409
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:259 → 308
    ELM2; ELM2 domain

  3. XM_047426266.1 → XP_047282222.1  mesoderm induction early response protein 1 isoform X10

  4. XM_017001928.3 → XP_016857417.1  mesoderm induction early response protein 1 isoform X6

    UniProtKB/Swiss-Prot
    Q8N108
    Conserved Domains (2) summary
    cd11661
    Location:287 → 331
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:181 → 230
    ELM2; ELM2 domain

  5. XM_047426256.1 → XP_047282212.1  mesoderm induction early response protein 1 isoform X3

  6. XM_047426263.1 → XP_047282219.1  mesoderm induction early response protein 1 isoform X5

  7. XM_047426255.1 → XP_047282211.1  mesoderm induction early response protein 1 isoform X3

  8. XM_017001924.2 → XP_016857413.1  mesoderm induction early response protein 1 isoform X5

    UniProtKB/Swiss-Prot
    Q8N108
    Conserved Domains (2) summary
    cd11661
    Location:305 → 349
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:199 → 248
    ELM2; ELM2 domain

  9. XM_017001919.2 → XP_016857408.1  mesoderm induction early response protein 1 isoform X2

    Conserved Domains (3) summary
    smart00717
    Location:324 → 369
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:324 → 368
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:218 → 267
    ELM2; ELM2 domain

  10. XM_047426260.1 → XP_047282216.1  mesoderm induction early response protein 1 isoform X5

  11. XM_017001931.2 → XP_016857420.1  mesoderm induction early response protein 1 isoform X8

    UniProtKB/Swiss-Prot
    Q8N108
    Conserved Domains (2) summary
    cd11661
    Location:261 → 305
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:155 → 204
    ELM2; ELM2 domain

  12. XM_047426264.1 → XP_047282220.1  mesoderm induction early response protein 1 isoform X7

  13. XM_017001927.2 → XP_016857416.1  mesoderm induction early response protein 1 isoform X6

    UniProtKB/Swiss-Prot
    Q8N108
    Conserved Domains (2) summary
    cd11661
    Location:287 → 331
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:181 → 230
    ELM2; ELM2 domain

  14. XM_047426265.1 → XP_047282221.1  mesoderm induction early response protein 1 isoform X9

  15. XM_017001920.2 → XP_016857409.1  mesoderm induction early response protein 1 isoform X2

    Conserved Domains (3) summary
    smart00717
    Location:324 → 369
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:324 → 368
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:218 → 267
    ELM2; ELM2 domain

  16. XM_017001930.2 → XP_016857419.1  mesoderm induction early response protein 1 isoform X7

    Conserved Domains (2) summary
    cd11661
    Location:287 → 331
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    pfam01448
    Location:181 → 230
    ELM2; ELM2 domain

  17. XM_017001933.2 → XP_016857422.1  mesoderm induction early response protein 1 isoform X9

  18. XM_017001934.2 → XP_016857423.1  mesoderm induction early response protein 1 isoform X9

RNA

  1. XR_007062438.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    66802518..66866111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054337911.1 → XP_054193886.1  mesoderm induction early response protein 1 isoform X4

  2. XM_054337908.1 → XP_054193883.1  mesoderm induction early response protein 1 isoform X1

  3. XM_054337921.1 → XP_054193896.1  mesoderm induction early response protein 1 isoform X10

  4. XM_054337914.1 → XP_054193889.1  mesoderm induction early response protein 1 isoform X6

  5. XM_054337912.1 → XP_054193887.1  mesoderm induction early response protein 1 isoform X5

  6. XM_054337913.1 → XP_054193888.1  mesoderm induction early response protein 1 isoform X5

  7. XM_054337910.1 → XP_054193885.1  mesoderm induction early response protein 1 isoform X3

  8. XM_054337909.1 → XP_054193884.1  mesoderm induction early response protein 1 isoform X2

  9. XM_054337917.1 → XP_054193892.1  mesoderm induction early response protein 1 isoform X8

  10. XM_054337920.1 → XP_054193895.1  mesoderm induction early response protein 1 isoform X2

  11. XM_054337916.1 → XP_054193891.1  mesoderm induction early response protein 1 isoform X6

  12. XM_054337915.1 → XP_054193890.1  mesoderm induction early response protein 1 isoform X7

  13. XM_054337918.1 → XP_054193893.1  mesoderm induction early response protein 1 isoform X9

  14. XM_054337919.1 → XP_054193894.1  mesoderm induction early response protein 1 isoform X9

RNA

  1. XR_008486129.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8N108.2 GenPept UniProtKB/Swiss-Prot:Q8N108

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools