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Nxph4 neurexophilin 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 59316, updated on 18-Sep-2024

Summary

Official Symbol
Nxph4provided by RGD
Official Full Name
neurexophilin 4provided by RGD
Primary source
RGD:628723
See related
EnsemblRapid:ENSRNOG00000025059 AllianceGenome:RGD:628723
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nph4
Summary
Predicted to enable signaling receptor binding activity. Predicted to be located in extracellular region. Orthologous to human NXPH4 (neurexophilin 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 11.0), Kidney (RPKM 7.9) and 1 other tissue See more
Orthologs
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Genomic context

See Nxph4 in Genome Data Viewer
Location:
7q22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (65253043..65261864, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (63367758..63376579, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (70833662..70842523, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene SH3 and cysteine rich domain 3 Neighboring gene NDUFA4, mitochondrial complex associated like 2 Neighboring gene serine hydroxymethyltransferase 2 Neighboring gene LDL receptor related protein 1 Neighboring gene uncharacterized LOC120093805 Neighboring gene uncharacterized LOC134479886

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in modulation of chemical synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in GABA-ergic synapse IEA
Inferred from Electronic Annotation
more info
 
is_active_in GABA-ergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021680.2NP_067712.2  neurexophilin-4 precursor

    See identical proteins and their annotated locations for NP_067712.2

    Status: PROVISIONAL

    Source sequence(s)
    BC081805
    UniProtKB/TrEMBL
    A0A0G2JSW7, A6HQW1
    Related
    ENSRNOP00000050310.2, ENSRNOT00000047449.5
    Conserved Domains (1) summary
    pfam06312
    Location:81303
    Neurexophilin; Neurexophilin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    65253043..65261864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)