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LOC6037551 acetylcholinesterase [ Culex quinquefasciatus (southern house mosquito) ]

Gene ID: 6037551, updated on 26-Mar-2024

Summary

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Gene symbol
LOC6037551
Gene description
acetylcholinesterase
See related
VectorBase:CQUJHB013404; EnsemblRapid:LOC6037551
Gene type
protein coding
RefSeq status
MODEL
Organism
Culex quinquefasciatus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Culicini; Culex; Culex
Also known as
AChE; ace1; AChE1; ace-1
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Genomic context

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See LOC6037551 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
100 current VPISU_Cqui_1.0_pri_paternal (GCF_015732765.1) 3 NC_051863.1 (71649064..71897754, complement)

Chromosome 3 - NC_051863.1Genomic Context describing neighboring genes Neighboring gene RING finger protein 44 Neighboring gene beta-catenin-like protein 1 Neighboring gene uncharacterized LOC6044862 Neighboring gene uncharacterized LOC6044863 Neighboring gene fibroblast growth factor receptor 3 Neighboring gene uncharacterized LOC119769399 Neighboring gene heparan sulfate 6-O-sulfotransferase Neighboring gene uncharacterized LOC119770226

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_051863.1 Chromosome 3 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Point mutations associated with organophosphate and carbamate resistance in Chinese strains of Culex pipiens quinquefasciatus (Diptera: Culicidae). Zhao M, et al. PLoS One, 2014. PMID 24788312, Free PMC Article
  2. First molecular genotyping of insensitive acetylcholinesterase associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia. Low VL, et al. Pest Manag Sci, 2013 Dec. PMID 23404830
  3. High incidence of ace-1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria. Alout H, et al. Insect Biochem Mol Biol, 2011 Jan. PMID 20887788
  4. Comparison of Anopheles gambiae and Culex pipiens acetycholinesterase 1 biochemical properties. Alout H, et al. Comp Biochem Physiol B Biochem Mol Biol, 2008 Jul. PMID 18455457
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Missense mutation in acetylcholinesterase are associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia.
    Title: First molecular genotyping of insensitive acetylcholinesterase associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia.
  2. There is high incidence of ace-1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria.
    Title: High incidence of ace-1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria.
  3. acetycholinesterase 1 (AChE1) belonging to both Anopheles gambiae and Culex pipiens seem to share identical properties.
    Title: Comparison of Anopheles gambiae and Culex pipiens acetycholinesterase 1 biochemical properties.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholinesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetylcholine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in choline metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetylcholinesterase
Names
acetylcholinesterase-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Culex quinquefasciatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Genomic

  1. NC_051863.1 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

    Range
    71649064..71897754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038261577.1 → XP_038117505.1  acetylcholinesterase isoform X2

    UniProtKB/TrEMBL
    V5W7Z2
    Related
    XP_038117505.1, XM_038261577.1
    Conserved Domains (1) summary
    pfam00135
    Location:137 → 659
    COesterase; Carboxylesterase family

  2. XM_038261578.1 → XP_038117506.1  acetylcholinesterase isoform X3

    UniProtKB/TrEMBL
    V5W7Z2
    Related
    XP_038117506.1, XM_038261578.1
    Conserved Domains (1) summary
    pfam00135
    Location:132 → 654
    COesterase; Carboxylesterase family

  3. XM_038261576.1 → XP_038117504.1  acetylcholinesterase isoform X1

    UniProtKB/TrEMBL
    V5W7Z2
    Related
    XP_038117504.1, XM_038261576.1
    Conserved Domains (1) summary
    pfam00135
    Location:140 → 662
    COesterase; Carboxylesterase family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q867X2.1 GenPept UniProtKB/Swiss-Prot:Q867X2

Gene LinkOut

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