Zfp551 zinc finger protein 551 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp551provided by MGI
Official Full Name: zinc finger protein 551provided by MGI
Primary source: MGI:MGI:3588205
See related: Ensembl:ENSMUSG00000034071 AllianceGenome:MGI:3588205
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Znf551; 9630004E07Rik
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF551 (zinc finger protein 551). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in CNS E18 (RPKM 2.0), whole brain E14.5 (RPKM 1.5) and 25 other tissues See more
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Genomic context

Location:: 7 A1; 7 7.5 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (12146476..12156685, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (12412549..12422739, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein 551

Names: zinc fingr protein 551

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033820.3 → NP_001028992.2 zinc finger protein 551

See identical proteins and their annotated locations for NP_001028992.2

Status: VALIDATED

Source sequence(s)

AC114404, AK137311, AW743849

Consensus CDS

CCDS20809.1

UniProtKB/Swiss-Prot

B2RUI1, Q3UVG7

Related

ENSMUSP00000079222.6, ENSMUST00000080348.12

Conserved Domains (3) summary

COG5048
Location:365 → 695

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:563 → 583

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:48 → 88

KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

12146476..12156685 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006540261.4 → XP_006540324.1 zinc finger protein 551 isoform X1

See identical proteins and their annotated locations for XP_006540324.1

Conserved Domains (2) summary

COG5048
Location:273 → 603

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:471 → 491

ZF_C2H2; C2H2 Zn finger [structural motif]
XM_006540260.4 → XP_006540323.1 zinc finger protein 551 isoform X1

See identical proteins and their annotated locations for XP_006540323.1

Conserved Domains (2) summary

COG5048
Location:273 → 603

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:471 → 491

ZF_C2H2; C2H2 Zn finger [structural motif]