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Mageb5b MAGE family member B5B [ Mus musculus (house mouse) ]

Gene ID: 629542, updated on 2-Nov-2024

Summary

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Official Symbol
Mageb5bprovided by MGI
Official Full Name
MAGE family member B5Bprovided by MGI
Primary source
MGI:MGI:3712084
See related
Ensembl:ENSMUSG00000064129 AllianceGenome:MGI:3712084
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm14781
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEB5 (MAGE family member B5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 2.7) See more
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Genomic context

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See Mageb5b in Genome Data Viewer
Location:
X C2; X 40.45 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (90667849..90679277)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (91624243..91635671)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene Gm5941 pseudogene Neighboring gene predicted gene, 46677 Neighboring gene MAGE family member B17, pseudogene Neighboring gene MAGE family member B5 Neighboring gene predicted gene, 46678

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. X-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility. Stark-Dykema ER, et al. Sci Rep, 2022 May 20. PMID 35595785, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
melanoma antigen, family B, 5-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205268.1 → NP_001192197.1  melanoma antigen, family B, 5-like

    See identical proteins and their annotated locations for NP_001192197.1

    Status: INFERRED

    Source sequence(s)
    AL627408
    Consensus CDS
    CCDS57768.1
    UniProtKB/TrEMBL
    A2A9Q9, Q9D9K4
    Related
    ENSMUSP00000077562.3, ENSMUST00000078469.3
    Conserved Domains (2) summary
    pfam01454
    Location:219 → 305
    MAGE; MAGE family
    pfam12440
    Location:5 → 80
    MAGE_N; Melanoma associated antigen family N terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    90667849..90679277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528231.3 → XP_006528294.1  melanoma antigen, family B, 5-like isoform X1

    See identical proteins and their annotated locations for XP_006528294.1

    UniProtKB/TrEMBL
    A2A9Q9, Q9D9K4
    Conserved Domains (2) summary
    pfam01454
    Location:219 → 305
    MAGE; MAGE family
    pfam12440
    Location:5 → 80
    MAGE_N; Melanoma associated antigen family N terminal
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.