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Abcb9 ATP binding cassette subfamily B member 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 63886, updated on 2-Nov-2024

Summary

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Official Symbol
Abcb9provided by RGD
Official Full Name
ATP binding cassette subfamily B member 9provided by RGD
Primary source
RGD:620254
See related
EnsemblRapid:ENSRNOG00000001082 AllianceGenome:RGD:620254
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tapl
Summary
Predicted to enable ABC-type transporter activity; ATP binding activity; and protein homodimerization activity. Predicted to be involved in peptide metabolic process; peptide transport; and transmembrane transport. Predicted to be located in endoplasmic reticulum membrane and lysosomal membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex. Predicted to be active in membrane. Orthologous to human ABCB9 (ATP binding cassette subfamily B member 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 60.2), Muscle (RPKM 37.6) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Abcb9 in Genome Data Viewer
Location:
12q15
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (38146659..38192862)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (32499213..32531932)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (37923974..37956678)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor like GTPase 6 interacting protein 4 Neighboring gene U6 spliceosomal RNA Neighboring gene 2-oxoglutarate and iron-dependent oxygenase domain containing 2 Neighboring gene uncharacterized LOC102552690 Neighboring gene keratin-associated protein 4-6-like Neighboring gene VPS37B subunit of ESCRT-I Neighboring gene huntingtin interacting protein 1 related

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The carboxyl terminal sequence of rat transporter associated with antigen processing (TAP)-like (ABCB9) is heterogeneous due to splicing of its mRNA. Yamaguchi Y, et al. Biol Pharm Bull, 2004 Jan. PMID 14709908
  2. An ABC transporter homologous to TAP proteins. Yamaguchi Y, et al. FEBS Lett, 1999 Aug 27. PMID 10471785
  3. Functional dissection of transmembrane domains of human TAP-like (ABCB9). Kamakura A, et al. Biochem Biophys Res Commun, 2008 Dec 19. PMID 18952056
  4. Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL). Zhao C, et al. J Biol Chem, 2008 Jun 20. PMID 18434309
  5. Identification of a lysosomal peptide transport system induced during dendritic cell development. Demirel O, et al. J Biol Chem, 2007 Dec 28. PMID 17977821

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ABC-type oligopeptide transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables ABC-type oligopeptide transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ABC-type peptide transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ABC-type peptide transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISO
Inferred from Sequence Orthology
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATPase-coupled transmembrane transporter activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
enables transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
NOT involved_in antigen processing and presentation of peptide antigen via MHC class I ISO
Inferred from Sequence Orthology
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in oligopeptide transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in peptide metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in peptide metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in peptide transport IEA
Inferred from Electronic Annotation
more info
  
involved_in peptide transport ISO
Inferred from Sequence Orthology
more info
  
involved_in peptide transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex TAS
Traceable Author Statement
more info
 PubMed 
NOT located_in early endosome ISO
Inferred from Sequence Orthology
more info
  
NOT located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
  
located_in lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in lysosome ISO
Inferred from Sequence Orthology
more info
  
located_in lysosome ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ABC-type oligopeptide transporter ABCB9
Names
ABC transporter 9 protein
ATP-binding cassette sub-family B member 9
ATP-binding cassette transporter 9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
ATP-binding cassette, subfamily B (MDR/TAP), member 9
TAP-like ABC transporter
TAP-like protein
NP_071574.1
XP_038945646.1
XP_063127680.1
XP_063127681.1
XP_063127682.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022238.3 → NP_071574.1  ABC-type oligopeptide transporter ABCB9

    See identical proteins and their annotated locations for NP_071574.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/Swiss-Prot
    Q764Q5, Q764Q6, Q9QYJ4
    UniProtKB/TrEMBL
    A0A0A0MY39, A6J117
    Related
    ENSRNOP00000096168.1, ENSRNOT00000098844.2
    Conserved Domains (3) summary
    cd03248
    Location:489 → 714
    ABCC_TAP; ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C
    TIGR00958
    Location:44 → 734
    3a01208; Conjugate Transporter-2 (CT2) Family protein
    pfam00664
    Location:189 → 451
    ABC_membrane; ABC transporter transmembrane region

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    38146659..38192862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063271610.1 → XP_063127680.1  ABC-type oligopeptide transporter ABCB9 isoform X1

    UniProtKB/Swiss-Prot
    Q764Q5, Q764Q6, Q9QYJ4
    UniProtKB/TrEMBL
    A6J117

  2. XM_063271612.1 → XP_063127682.1  ABC-type oligopeptide transporter ABCB9 isoform X4

  3. XM_063271611.1 → XP_063127681.1  ABC-type oligopeptide transporter ABCB9 isoform X3

    Related
    ENSRNOP00000083417.1, ENSRNOT00000114288.2

  4. XM_039089718.2 → XP_038945646.1  ABC-type oligopeptide transporter ABCB9 isoform X2

    Conserved Domains (1) summary
    TIGR00958
    Location:35 → 572
    3a01208; Conjugate Transporter-2 (CT2) Family protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9QYJ4.1 GenPept UniProtKB/Swiss-Prot:Q9QYJ4

Gene LinkOut

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