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poml-3 SMP-30/Gluconolactonase/LRE-like region domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 6418581, updated on 2-Nov-2024

Summary

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Official Symbol
poml-3
Official Full Name
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Primary source
WormBase:WBGene00077701
Locus tag
CELE_E01A2.10
See related
AllianceGenome:WB:WBGene00077701
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); dementia (multiple); eye disease (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Orthologous to human PON1 (paraoxonase 1); PON2 (paraoxonase 2); and PON3 (paraoxonase 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See poml-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (4145315..4147121, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Akirin Neighboring gene ncRNA Neighboring gene GCS light chain Neighboring gene Arylesterase Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increasing Complexity of the N-Glycome During Caenorhabditis Development. Wilson IBH, et al. Mol Cell Proteomics, 2023 Mar. PMID 36717059, Free PMC Article
  2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  3. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  4. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
  5. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
NP_001122440.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    4145315..4147121 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001128968.4 → NP_001122440.1  SMP-30/Gluconolactonase/LRE-like region domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122440.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B1V898
    Conserved Domains (1) summary
    COG3386
    Location:109 → 282
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
Nucleotide Protein
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