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POU5F1P3 POU class 5 homeobox 1 pseudogene 3 [ Homo sapiens (human) ]

Gene ID: 642559, updated on 28-Oct-2024

Summary

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Official Symbol
POU5F1P3provided by HGNC
Official Full Name
POU class 5 homeobox 1 pseudogene 3provided by HGNC
Primary source
HGNC:HGNC:9222
See related
Ensembl:ENSG00000235602 AllianceGenome:HGNC:9222
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OCT3; OCT4; OTF3; OTF-3; OTF3L; Oct-3; Oct-4; POU5F1; POU5F1L; OCT4-pg3; POU5FLC12
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See POU5F1P3 in Genome Data Viewer
Location:
12p13.31
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (8133769..8134852, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (8147349..8148432, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (8286365..8287448, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene complement C3a receptor 1 Neighboring gene NANOG hESC enhancer GRCh37_chr12:8229725-8230226 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:8234132-8235331 Neighboring gene NECAP endocytosis associated 1 Neighboring gene C-type lectin domain family 4 member A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5929 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:8286281-8287059 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:8294369-8294870 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:8296489-8296988 Neighboring gene GCSH pseudogene 4 Neighboring gene zinc finger protein 705A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In situ hybridization localizes the human OTF3 to chromosome 6p21.3-->p22 and OTF3L to 12p13. Guillaudeux T, et al. Cytogenet Cell Genet, 1993. PMID 8500351
  2. Oct4 and its pseudogenes confuse stem cell research. Liedtke S, et al. Cell Stem Cell, 2007 Oct 11. PMID 18371374
  3. Expression and differentiation between OCT4A and its Pseudogenes in human ESCs and differentiated adult somatic cells. Jez M, et al. PLoS One, 2014. PMID 24586860, Free PMC Article
  4. Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer. Wezel F, et al. Am J Pathol, 2013 Oct. PMID 23933063
  5. Multiple retropseudogenes from pluripotent cell-specific gene expression indicates a potential signature for novel gene identification. Pain D, et al. J Biol Chem, 2005 Feb 25. PMID 15640145

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • Octamer-binding protein 3
  • Octamer-binding protein 4
  • Octamer-binding transcription factor 3
  • POU domain class 5, transcription factor 1 pseudogene 3
  • POU domain transcription factor OCT4-pg3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036440.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC092111, GU480907
    Related
    ENST00000428824.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    8133769..8134852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    8147349..8148432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_005793.7: Suppressed sequence

    Description
    NG_005793.7: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.

  2. NG_023971.1: Suppressed sequence

    Description
    NG_023971.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.
Nucleotide Protein
Heading Accession and Version

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