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Or6a2 olfactory receptor family 6 subfamily A member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 65140, updated on 10-Jul-2024

Summary

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Official Symbol
Or6a2provided by RGD
Official Full Name
olfactory receptor family 6 subfamily A member 2provided by RGD
Primary source
RGD:68340
See related
EnsemblRapid:ENSRNOG00000085613 AllianceGenome:RGD:68340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Olfr41; Olr226
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
human mouse all
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Genomic context

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See Or6a2 in Genome Data Viewer
Location:
1q33
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (170239077..170240060, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (160827258..160828241, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (148846679..148847662, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134484910 Neighboring gene olfactory receptor family 6 subfamily B member 6 Neighboring gene olfactory receptor family 6 subfamily I member 2, pseudogene 1 Neighboring gene olfactory receptor family 10 subfamily A member 5 Neighboring gene transfer RNA alanine (anticodon AGC) 48

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and expression of odorant receptors. Raming K, et al. Nature, 1993 Jan 28. PMID 7678922
  2. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Buck L, et al. Cell, 1991 Apr 5. PMID 1840504
  3. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
olfactory receptor 226
Names
olfactory receptor 41
olfactory receptor-like protein I7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031710.2 → NP_113898.2  olfactory receptor 226

    Status: REVIEWED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    P23270
    UniProtKB/TrEMBL
    A0A8I6AW64, A6I7Q8
    Related
    ENSRNOP00000102048.1, ENSRNOT00000139670.1
    Conserved Domains (1) summary
    cd15224
    Location:26 → 299
    7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    170239077..170240060 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23270.2 GenPept UniProtKB/Swiss-Prot:P23270

Gene LinkOut

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