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ripply1 - ripply transcriptional repressor 1

Involved in negative regulation of DNA-templated transcription and somite rostral/caudal axis specification. Acts upstream of or within regulation of skeletal muscle tissue development and somite specification. Located in nucleus. Is expressed in several structures, including margin; paraxial mesoderm; presumptive paraxial mesoderm; shield; and somite. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 6. Orthologous to several human genes including RIPPLY2 (ripply transcriptional repressor 2). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa