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SLC19A1 solute carrier family 19 member 1 [ Homo sapiens (human) ]

Gene ID: 6573, updated on 3-Nov-2024

Summary

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Official Symbol
SLC19A1provided by HGNC
Official Full Name
solute carrier family 19 member 1provided by HGNC
Primary source
HGNC:HGNC:10937
See related
Ensembl:ENSG00000173638 MIM:600424; AllianceGenome:HGNC:10937
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RFC; CHMD; FOLT; IFC1; REFC; RFC1; hRFC; IFC-1; MEGAF; RFT-1; IMD114; hSLC19A1
Summary
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Annotation information
Note: RFC1 (GeneID: 5981) and SLC19A1 (GeneID: 6573) share the RFC1 symbol/alias in common. RFC1 is the official symbol for the gene name 'replication factor C subunit 1' and is an alias for 'reduced folate carrier 1' on the 'solute carrier family 19 member 1' gene. [18 May 2018]
Expression
Ubiquitous expression in liver (RPKM 10.8), placenta (RPKM 8.5) and 25 other tissues See more
Orthologs
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Genomic context

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See SLC19A1 in Genome Data Viewer
Location:
21q22.3
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (45502517..45563025, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (43870718..43932046, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (46932461..46982939, complement)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905042 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46858777-46859506 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46859507-46860236 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46860237-46860966 Neighboring gene collagen type XVIII alpha 1 chain Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46862147-46862656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46870853-46871354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46871355-46871854 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46874827-46875383 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46885176-46885740 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46885741-46886304 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18590 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46894762-46895262 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46908672-46909202 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46912122-46912622 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46934825-46935332 Neighboring gene microRNA 6815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46935840-46936346 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18591 Neighboring gene Sharpr-MPRA regulatory region 1559 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:46948644-46948814 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46954106-46954980 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13402 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13403 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46962482-46962994 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:46970045-46970201 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13405 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13406 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46975660-46976554 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46980259-46980968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46998853-46999354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47001008-47001944 Neighboring gene uncharacterized LOC107985485 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47009554-47010054 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13407 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13408 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13409 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47015623-47016124 Neighboring gene Sharpr-MPRA regulatory region 7423 Neighboring gene MPRA-validated peak4424 silencer Neighboring gene MPRA-validated peak4426 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47031725-47032226 Neighboring gene long intergenic non-protein coding RNA 1694 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:47053121-47054320 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18594 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18595 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47057095-47057612 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13410 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13411 Neighboring gene poly(rC) binding protein 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:47204393-47205264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47236921-47237422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47237423-47237922 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:47241669-47242354 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:47244540-47245132 Neighboring gene MPRA-validated peak4427 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:47255439-47255946 Neighboring gene PCBP3 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Effects of a microRNA binding site polymorphism in SLC19A1 on methotrexate concentrations in Chinese children with acute lymphoblastic leukemia. Wang SM, et al. Med Oncol, 2014 Jul. PMID 24927955
  2. [Epidemiological study on reduced folate carrier gene(RFC1 A80G) polymorphism and other risk factors of neural tube defects]. Pei LJ, et al. Beijing Da Xue Xue Bao Yi Xue Ban, 2005 Aug 18. PMID 16086047
  3. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Pei L, et al. Ann Epidemiol, 2006 May. PMID 16019224
  4. Polymorphism G80A in the reduced folate carrier gene and its relationship to survival and risk of relapse in acute lymphoblastic leukemia. Leyva-Vázquez MA, et al. J Investig Med, 2012 Oct. PMID 22914600
  5. Reduced folate carrier A80G polymorphism and susceptibility to neural tube defects: a meta-analysis. Wang HG, et al. Gene, 2012 Dec 1. PMID 22975209

See all (311) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
    Title: Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
  2. Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults.
    Title: Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults.
  3. Correlation between methylation level of the SLC19A1 promoter region and methotrexate metabolism in adult acute lymphoblastic leukemia.
    Title: Correlation between methylation level of the SLC19A1 promoter region and methotrexate metabolism in adult acute lymphoblastic leukemia.
  4. Genetic aetiology of Down syndrome birth: novel variants of maternal DNMT3B and RFC1 genes increase risk of meiosis II nondisjunction in the oocyte.
    Title: Genetic aetiology of Down syndrome birth: novel variants of maternal DNMT3B and RFC1 genes increase risk of meiosis II nondisjunction in the oocyte.
  5. Recognition of cyclic dinucleotides and folates by human SLC19A1.
    Title: Recognition of cyclic dinucleotides and folates by human SLC19A1.
  6. Methotrexate recognition by the human reduced folate carrier SLC19A1.
    Title: Methotrexate recognition by the human reduced folate carrier SLC19A1.
  7. SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.
    Title: SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.
  8. Hypoxia-Immune-Related Gene SLC19A1 Serves as a Potential Biomarker for Prognosis in Multiple Myeloma.
    Title: Hypoxia-Immune-Related Gene SLC19A1 Serves as a Potential Biomarker for Prognosis in Multiple Myeloma.
  9. The transcriptome profile of human trisomy 21 blood cells.
    Title: The transcriptome profile of human trisomy 21 blood cells.
  10. Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability.
    Title: Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability.
Submit: New GeneRIF Correction See all GeneRIFs (176)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Immunodeficiency 114, folate-responsive
MedGen: C5882719 OMIM: 620603 GeneReviews: Not available
not available
Megaloblastic anemia, folate-responsive
MedGen: C2749656 OMIM: 601775 GeneReviews: Not available
Compare labs

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Replication interactions

Interaction Pubs
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of SLC19A1 PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 2',3'-cyclic GMP-AMP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables antiporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cyclic-GMP-AMP transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables folate:monoatomic anion antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables folate:monoatomic anion antiporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables folate:monoatomic anion antiporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables folic acid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables folic acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables folic acid transmembrane transporter activity TAS
Traceable Author Statement
more info
  
enables methotrexate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables organic anion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables xenobiotic transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in cyclic-GMP-AMP transmembrane import across plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in female pregnancy IEA
Inferred from Electronic Annotation
more info
  
involved_in folate import across plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in folate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in folate transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in folic acid metabolic process TAS
Traceable Author Statement
more info
  
involved_in folic acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in folic acid transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in methotrexate transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in monoatomic anion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic anion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of cGAS/STING signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transport across blood-brain barrier NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transport across blood-brain barrier TAS
Traceable Author Statement
more info
 PubMed 
involved_in xenobiotic transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in basolateral plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in brush border membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
reduced folate transporter
Names
cyclic dinucleotide:anion antiporter SLC19A1
folate transporter 1
folate:anion antiporter SLC19A1
intestinal folate carrier 1
placental folate transporter
reduced folate carrier 1
reduced folate carrier protein
reduced folate transporter 1
solute carrier family 19 (folate transporter), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_028278.2 RefSeqGene

    Range
    25704..55579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001205206.4 → NP_001192135.1  reduced folate transporter isoform 2

    Status: REVIEWED

    Source sequence(s)
    AK307623, AK313125, BC003068, BC023005, BX322561
    Consensus CDS
    CCDS56218.1
    UniProtKB/Swiss-Prot
    P41440
    Related
    ENSP00000369347.4, ENST00000380010.8
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 431
    rfc; RFC reduced folate carrier

  2. NM_001205207.3 → NP_001192136.1  reduced folate transporter isoform 3

    See identical proteins and their annotated locations for NP_001192136.1

    Status: REVIEWED

    Source sequence(s)
    AK303168, BC023005, BX322561, DC311922, U19720
    Consensus CDS
    CCDS56217.1
    UniProtKB/Swiss-Prot
    P41440
    Related
    ENSP00000441772.1, ENST00000485649.3
    Conserved Domains (1) summary
    TIGR00806
    Location:23 → 466
    rfc; RFC reduced folate carrier

  3. NM_001352510.2 → NP_001339439.1  reduced folate transporter isoform 4

    Status: REVIEWED

    Source sequence(s)
    BC023005, BX322561
    Conserved Domains (1) summary
    cl27502
    Location:1 → 388
    Folate_carrier; Reduced folate carrier

  4. NM_001352511.3 → NP_001339440.1  reduced folate transporter isoform 2

    Status: REVIEWED

    Source sequence(s)
    BC023005, BX322561
    Consensus CDS
    CCDS56218.1
    Related
    ENSP00000498221.1, ENST00000650808.1
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 431
    rfc; RFC reduced folate carrier

  5. NM_001352512.2 → NP_001339441.1  reduced folate transporter isoform 1

    Status: REVIEWED

    Source sequence(s)
    BC023005, BX322561
    Consensus CDS
    CCDS13725.1
    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 506
    rfc; RFC reduced folate carrier

  6. NM_194255.4 → NP_919231.1  reduced folate transporter isoform 1

    See identical proteins and their annotated locations for NP_919231.1

    Status: REVIEWED

    Source sequence(s)
    AK307623, AK313125, BC023005, BX322561, U19720
    Consensus CDS
    CCDS13725.1
    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
    Related
    ENSP00000308895.4, ENST00000311124.9
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 506
    rfc; RFC reduced folate carrier

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    45502517..45563025 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047440963.1 → XP_047296919.1  reduced folate transporter isoform X11

  2. XM_047440964.1 → XP_047296920.1  reduced folate transporter isoform X11

  3. XM_047440957.1 → XP_047296913.1  reduced folate transporter isoform X5

  4. XM_047440960.1 → XP_047296916.1  reduced folate transporter isoform X8

  5. XM_047440955.1 → XP_047296911.1  reduced folate transporter isoform X3

  6. XM_047440965.1 → XP_047296921.1  reduced folate transporter isoform X12

  7. XM_047440962.1 → XP_047296918.1  reduced folate transporter isoform X10

  8. XM_047440961.1 → XP_047296917.1  reduced folate transporter isoform X9

  9. XM_011529700.3 → XP_011528002.1  reduced folate transporter isoform X6

    See identical proteins and their annotated locations for XP_011528002.1

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 506
    rfc; RFC reduced folate carrier

  10. XM_047440954.1 → XP_047296910.1  reduced folate transporter isoform X2

  11. XM_011529696.3 → XP_011527998.1  reduced folate transporter isoform X2

    See identical proteins and their annotated locations for XP_011527998.1

    Conserved Domains (1) summary
    TIGR00806
    Location:98 → 603
    rfc; RFC reduced folate carrier

  12. XM_017028443.2 → XP_016883932.2  reduced folate transporter isoform X6

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

  13. XM_011529702.3 → XP_011528004.1  reduced folate transporter isoform X6

    See identical proteins and their annotated locations for XP_011528004.1

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 506
    rfc; RFC reduced folate carrier

  14. XM_047440958.1 → XP_047296914.1  reduced folate transporter isoform X6

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

  15. XM_011529698.3 → XP_011528000.1  reduced folate transporter isoform X1

    See identical proteins and their annotated locations for XP_011528000.1

    Conserved Domains (1) summary
    TIGR00806
    Location:23 → 528
    rfc; RFC reduced folate carrier

  16. XM_011529703.3 → XP_011528005.1  reduced folate transporter isoform X6

    See identical proteins and their annotated locations for XP_011528005.1

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8
    Conserved Domains (1) summary
    TIGR00806
    Location:1 → 506
    rfc; RFC reduced folate carrier

  17. XM_047440956.1 → XP_047296912.1  reduced folate transporter isoform X4

  18. XM_047440959.1 → XP_047296915.1  reduced folate transporter isoform X7

  19. XM_011529706.4 → XP_011528008.1  reduced folate transporter isoform X7

    Conserved Domains (1) summary
    TIGR00806
    Location:18 → 460
    rfc; RFC reduced folate carrier

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791815.1 Reference GRCh38.p14 PATCHES

    Range
    119752..180251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333325.1 → XP_054189300.1  reduced folate transporter isoform X11

  2. XM_054333326.1 → XP_054189301.1  reduced folate transporter isoform X11

  3. XM_054333315.1 → XP_054189290.1  reduced folate transporter isoform X5

  4. XM_054333313.1 → XP_054189288.1  reduced folate transporter isoform X3

  5. XM_054333321.1 → XP_054189296.1  reduced folate transporter isoform X8

  6. XM_054333327.1 → XP_054189302.1  reduced folate transporter isoform X12

  7. XM_054333324.1 → XP_054189299.1  reduced folate transporter isoform X10

  8. XM_054333322.1 → XP_054189297.1  reduced folate transporter isoform X9

  9. XM_054333323.1 → XP_054189298.1  reduced folate transporter isoform X6

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

  10. XM_054333310.1 → XP_054189285.1  reduced folate transporter isoform X2

  11. XM_054333311.1 → XP_054189286.1  reduced folate transporter isoform X2

  12. XM_054333312.1 → XP_054189287.1  reduced folate transporter isoform X2

  13. XM_054333316.1 → XP_054189291.1  reduced folate transporter isoform X6

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

  14. XM_054333318.1 → XP_054189293.1  reduced folate transporter isoform X6

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

  15. XM_054333309.1 → XP_054189284.1  reduced folate transporter isoform X1

  16. XM_054333317.1 → XP_054189292.1  reduced folate transporter isoform X6

    UniProtKB/Swiss-Prot
    B2R7U8, B7Z8C3, E9PFY4, O00553, O60227, P41440, Q13026, Q9BTX8

  17. XM_054333314.1 → XP_054189289.1  reduced folate transporter isoform X4

  18. XM_054333320.1 → XP_054189295.1  reduced folate transporter isoform X7

  19. XM_054333319.1 → XP_054189294.1  reduced folate transporter isoform X7

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    43870718..43932046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054324804.1 → XP_054180779.1  reduced folate transporter isoform X11

  2. XM_054324805.1 → XP_054180780.1  reduced folate transporter isoform X11

  3. XM_054324794.1 → XP_054180769.1  reduced folate transporter isoform X5

  4. XM_054324792.1 → XP_054180767.1  reduced folate transporter isoform X3

  5. XM_054324800.1 → XP_054180775.1  reduced folate transporter isoform X8

  6. XM_054324806.1 → XP_054180781.1  reduced folate transporter isoform X12

  7. XM_054324803.1 → XP_054180778.1  reduced folate transporter isoform X10

  8. XM_054324801.1 → XP_054180776.1  reduced folate transporter isoform X9

  9. XM_054324802.1 → XP_054180777.1  reduced folate transporter isoform X6

  10. XM_054324789.1 → XP_054180764.1  reduced folate transporter isoform X2

  11. XM_054324790.1 → XP_054180765.1  reduced folate transporter isoform X2

  12. XM_054324791.1 → XP_054180766.1  reduced folate transporter isoform X2

  13. XM_054324795.1 → XP_054180770.1  reduced folate transporter isoform X6

  14. XM_054324797.1 → XP_054180772.1  reduced folate transporter isoform X6

  15. XM_054324788.1 → XP_054180763.1  reduced folate transporter isoform X1

  16. XM_054324796.1 → XP_054180771.1  reduced folate transporter isoform X6

  17. XM_054324793.1 → XP_054180768.1  reduced folate transporter isoform X4

  18. XM_054324799.1 → XP_054180774.1  reduced folate transporter isoform X7

  19. XM_054324798.1 → XP_054180773.1  reduced folate transporter isoform X7

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_003056.2: Suppressed sequence

    Description
    NM_003056.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41440.3 GenPept UniProtKB/Swiss-Prot:P41440

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