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Susd3 sushi domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 66329, updated on 28-Oct-2024

Summary

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Official Symbol
Susd3provided by MGI
Official Full Name
sushi domain containing 3provided by MGI
Primary source
MGI:MGI:1913579
See related
Ensembl:ENSMUSG00000021384 AllianceGenome:MGI:1913579
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700017I11Rik; 2810440J20Rik
Summary
Predicted to be active in plasma membrane. Is expressed in retina outer nuclear layer and urinary system. Orthologous to human SUSD3 (sushi domain containing 3). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in ovary adult (RPKM 50.4), adrenal adult (RPKM 21.7) and 5 other tissues See more
Orthologs
human all
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Genomic context

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See Susd3 in Genome Data Viewer
Location:
13 A5; 13 25.16 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (49378993..49402197, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (49230511..49248706, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene ninjurin 1 Neighboring gene STARR-positive B cell enhancer ABC_E7237 Neighboring gene caspase recruitment domain family, member 19 Neighboring gene STARR-positive B cell enhancer ABC_E5396 Neighboring gene predicted gene, 52024 Neighboring gene STARR-positive B cell enhancer ABC_E8525 Neighboring gene STARR-positive B cell enhancer ABC_E8526 Neighboring gene STARR-positive B cell enhancer mm9_chr13:49346365-49346665 Neighboring gene RIKEN cDNA E030007A22 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:49363145-49363298 Neighboring gene FYVE, RhoGEF and PH domain containing 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:49402581-49402764 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:49402849-49403036 Neighboring gene STARR-positive B cell enhancer ABC_E4067 Neighboring gene BICD cargo adaptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. Nakano Y, et al. PLoS Genet, 2012. PMID 23055939, Free PMC Article
  2. Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. Thiagarajan RD, et al. PLoS One, 2011 Feb 28. PMID 21386911, Free PMC Article
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
sushi domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360772.2 → NP_001347701.1  sushi domain-containing protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC140284

  2. NM_025491.5 → NP_079767.2  sushi domain-containing protein 3 isoform 1

    See identical proteins and their annotated locations for NP_079767.2

    Status: VALIDATED

    Source sequence(s)
    AC140284
    Consensus CDS
    CCDS26498.1
    UniProtKB/Swiss-Prot
    Q80XL5, Q9CYV1, Q9D176, Q9DA86
    Related
    ENSMUSP00000061423.7, ENSMUST00000058196.13
    Conserved Domains (1) summary
    cd00033
    Location:32 → 92
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  3. NM_028340.3 → NP_082616.1  sushi domain-containing protein 3 isoform 2

    See identical proteins and their annotated locations for NP_082616.1

    Status: VALIDATED

    Source sequence(s)
    AC140284
    Consensus CDS
    CCDS56880.1
    UniProtKB/Swiss-Prot
    Q9D176
    Related
    ENSMUSP00000021816.6, ENSMUST00000021816.12
    Conserved Domains (1) summary
    cd00033
    Location:20 → 80
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    49378993..49402197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158106.1 → XP_036013999.1  sushi domain-containing protein 3 isoform X5

    Conserved Domains (1) summary
    cd00033
    Location:41 → 101
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  2. XM_036158105.1 → XP_036013998.1  sushi domain-containing protein 3 isoform X3

  3. XM_036158103.1 → XP_036013996.1  sushi domain-containing protein 3 isoform X1

    Conserved Domains (1) summary
    cd00033
    Location:41 → 101
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  4. XM_036158104.1 → XP_036013997.1  sushi domain-containing protein 3 isoform X2

    Conserved Domains (1) summary
    cd00033
    Location:32 → 92
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  5. XM_006516940.5 → XP_006517003.1  sushi domain-containing protein 3 isoform X4

    Conserved Domains (2) summary
    cd00033
    Location:41 → 101
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd21533
    Location:106 → 142
    MERS-CoV-like_E; Middle East respiratory syndrome-related coronavirus Envelope small membrane protein and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D176.1 GenPept UniProtKB/Swiss-Prot:Q9D176

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