Pcp4l1 Purkinje cell protein 4-like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pcp4l1provided by MGI
Official Full Name: Purkinje cell protein 4-like 1provided by MGI
Primary source: MGI:MGI:1913675
See related: Ensembl:ENSMUSG00000038370 AllianceGenome:MGI:1913675
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1500036F01Rik
Summary: Is expressed in several structures, including alimentary system; brain; cardiovascular system; future midbrain; and genitourinary system. Orthologous to human PCP4L1 (Purkinje cell protein 4 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in bladder adult (RPKM 127.1), frontal lobe adult (RPKM 122.5) and 13 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 H3; 1 79.11 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (171000833..171023837, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (171173264..171196268, complement)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pcp4l1 is an activity-dependent gene in mouse olfactory sensory neurons. [Pcp4l1]
Title: Activity-dependent genes in mouse olfactory sensory neurons.
We speculate Pcp4l1 may be a latent calmodulin inhibitor regulated by post-translational modification and/or co-factor interactions
Title: Pcp4l1 contains an auto-inhibitory element that prevents its IQ motif from binding to calmodulin.
Pcp4l1 encodes a polypeptide with significant sequence similarity to the Purkinje cell protein 4 gene (Pcp40;it is expressed during mouse development.
Title: Pcp4l1, a novel gene encoding a Pcp4-like polypeptide, is expressed in specific domains of the developing brain.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:234265

NoName (e-PCR)
- UniSTS:493049

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: Purkinje cell protein 4-like protein 1

Names: PCP4-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.