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Oip5os1 Opa interacting protein 5, opposite strand 1 [ Mus musculus (house mouse) ]

Gene ID: 66602, updated on 28-Oct-2024

Summary

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Official Symbol
Oip5os1provided by MGI
Official Full Name
Opa interacting protein 5, opposite strand 1provided by MGI
Primary source
MGI:MGI:1913852
See related
Ensembl:ENSMUSG00000085438 AllianceGenome:MGI:1913852
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cyrano; Oip5as1; linc-oip5; 1190006L01Rik; 1700020I14Rik; 4933437I03Rik
Summary
Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; brain; and hemolymphoid system gland. [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in cerebellum adult (RPKM 14.6), heart adult (RPKM 11.0) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Oip5os1 in Genome Data Viewer
Location:
2 E5; 2 59.97 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (119424777..119431227)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (119594296..119600746)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 33412 Neighboring gene exonuclease 3'-5' domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E2639 Neighboring gene STARR-positive B cell enhancer ABC_E5970 Neighboring gene calcineurin-like EF hand protein 1 Neighboring gene STARR-seq mESC enhancer starr_05487 Neighboring gene STARR-positive B cell enhancer ABC_E1008 Neighboring gene STARR-positive B cell enhancer mm9_chr2:119444191-119444492 Neighboring gene Opa interacting protein 5 Neighboring gene nucleolar and spindle associated protein 1 Neighboring gene nuclear encoded rRNA 5S 204

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Deletion of the muscle enriched lncRNA Oip5os1 induces atrial dysfunction in male mice with diabetes. Zhuang A, et al. Physiol Rep, 2023 Dec. PMID 38054572, Free PMC Article
  2. OIP5-AS1 Attenuates Microangiopathy in Diabetic Mouse by Regulating miR-200b/ACE2. Xie W, et al. World Neurosurg, 2020 Jul. PMID 32200014
  3. The Long Non-coding RNA Cyrano Is Dispensable for Pluripotency of Murine and Human Pluripotent Stem Cells. Hunkler HJ, et al. Stem Cell Reports, 2020 Jul 14. PMID 32531193, Free PMC Article
  4. lncRNA Oip5-as1 inhibits excessive mitochondrial fission in myocardial ischemia/reperfusion injury by modulating DRP1 phosphorylation. Niu X, et al. Cell Mol Biol Lett, 2024 May 14. PMID 38745296, Free PMC Article
  5. Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410. Sun WL, et al. Biosci Rep, 2019 Jan 31. PMID 30498093, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. lncRNA Oip5-as1 inhibits excessive mitochondrial fission in myocardial ischemia/reperfusion injury by modulating DRP1 phosphorylation.
    Title: lncRNA Oip5-as1 inhibits excessive mitochondrial fission in myocardial ischemia/reperfusion injury by modulating DRP1 phosphorylation.
  2. Deletion of the muscle enriched lncRNA Oip5os1 induces atrial dysfunction in male mice with diabetes.
    Title: Deletion of the muscle enriched lncRNA Oip5os1 induces atrial dysfunction in male mice with diabetes.
  3. The Long Non-coding RNA Cyrano Is Dispensable for Pluripotency of Murine and Human Pluripotent Stem Cells.
    Title: The Long Non-coding RNA Cyrano Is Dispensable for Pluripotency of Murine and Human Pluripotent Stem Cells.
  4. OIP5-AS1 Attenuates Microangiopathy in Diabetic Mouse by Regulating miR-200b/ACE2.
    Title: OIP5-AS1 Attenuates Microangiopathy in Diabetic Mouse by Regulating miR-200b/ACE2.
  5. these results provide new insights into the regulation between 1700020I14Rik and miR-34a-5p/Sirt1/HIF-1alpha signaling pathway during the progression of diabetic nephropathy.
    Title: LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.
  6. Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410.
    Title: Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_015473.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AI841061, AK006166, AK017100
    Related
    ENSMUST00000328666.1

  2. NR_027832.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternative donor splice site at an internal coding exon, and thus is shorter than variant 1.
    Source sequence(s)
    AI841061, AK017100
    Related
    ENSMUST00000241192.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    119424777..119431227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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