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Swt1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) [ Mus musculus (house mouse) ]

Gene ID: 66875, updated on 28-Oct-2024

Summary

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Official Symbol
Swt1provided by MGI
Official Full Name
SWT1 RNA endoribonuclease homolog (S. cerevisiae)provided by MGI
Primary source
MGI:MGI:1914125
See related
Ensembl:ENSMUSG00000052748 AllianceGenome:MGI:1914125
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C1orf26; 1200016B10Rik
Summary
Predicted to be active in nucleus. Is expressed in pancreas epithelium. Orthologous to human SWT1 (SWT1 RNA endoribonuclease homolog). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 11.5), CNS E11.5 (RPKM 4.5) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Swt1 in Genome Data Viewer
Location:
1 G1; 1 64.08 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (151243449..151304248, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (151367698..151428497, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4356 Neighboring gene STARR-seq mESC enhancer starr_02612 Neighboring gene predicted gene, 46162 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:153134717-153134870 Neighboring gene STARR-seq mESC enhancer starr_02614 Neighboring gene STARR-seq mESC enhancer starr_02615 Neighboring gene predicted gene 10138 Neighboring gene STARR-positive B cell enhancer ABC_E3312 Neighboring gene STARR-positive B cell enhancer mm9_chr1:153191350-153191651 Neighboring gene STARR-positive B cell enhancer ABC_E3313 Neighboring gene influenza virus NS1A binding protein Neighboring gene STARR-positive B cell enhancer ABC_E994 Neighboring gene STARR-positive B cell enhancer ABC_E5817 Neighboring gene STARR-seq mESC enhancer starr_02618 Neighboring gene tRNA methyltransferase 1 like Neighboring gene STARR-seq mESC enhancer starr_02619 Neighboring gene microRNA 7682 Neighboring gene ring finger protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transcriptional protein SWT1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025819.4 → NP_080095.3  transcriptional protein SWT1

    See identical proteins and their annotated locations for NP_080095.3

    Status: VALIDATED

    Source sequence(s)
    AC165946, AK004803, BY062718, CV563132
    Consensus CDS
    CCDS15360.1
    UniProtKB/Swiss-Prot
    E9QP79, Q6PAN2, Q7TMQ6, Q9DBQ9
    Related
    ENSMUSP00000067516.6, ENSMUST00000064771.12
    Conserved Domains (1) summary
    cd09880
    Location:396 → 540
    PIN_Smg5-Smg6-like; PIN domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    151243449..151304248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248058.2 → XP_011246360.1  transcriptional protein SWT1 isoform X1

    Conserved Domains (1) summary
    cd18727
    Location:150 → 289
    PIN_Swt1-like; VapC-like PIN domain of Saccharomyces cerevisiae Swt1p, human SWT1 and related proteins

  2. XM_030242199.2 → XP_030098059.1  transcriptional protein SWT1 isoform X2

    Conserved Domains (1) summary
    cd18727
    Location:2 → 139
    PIN_Swt1-like; VapC-like PIN domain of Saccharomyces cerevisiae Swt1p, human SWT1 and related proteins

  3. XM_011248059.3 → XP_011246361.1  transcriptional protein SWT1 isoform X2

    Conserved Domains (1) summary
    cd18727
    Location:2 → 139
    PIN_Swt1-like; VapC-like PIN domain of Saccharomyces cerevisiae Swt1p, human SWT1 and related proteins

RNA

  1. XR_004934079.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DBQ9.3 GenPept UniProtKB/Swiss-Prot:Q9DBQ9

Gene LinkOut

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