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Golt1b golgi transport 1B [ Mus musculus (house mouse) ]

Gene ID: 66964, updated on 28-Oct-2024

Summary

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Official Symbol
Golt1bprovided by MGI
Official Full Name
golgi transport 1Bprovided by MGI
Primary source
MGI:MGI:1914214
See related
Ensembl:ENSMUSG00000030245 AllianceGenome:MGI:1914214
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CGI-141; 2310061A22Rik
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein transport; and retrograde transport, endosome to Golgi. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in orbito-sphenoid. Orthologous to human GOLT1B (golgi transport 1B). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 11.2), limb E14.5 (RPKM 10.4) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Golt1b in Genome Data Viewer
Location:
6 G2; 6 73.98 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142332929..142349584)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142387211..142413835)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family, member 1a5 Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E6502 Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene RecQ protein-like Neighboring gene STARR-positive B cell enhancer ABC_E1716 Neighboring gene spexin hormone Neighboring gene glycogen synthase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. ZMPSTE24 defends against influenza and other pathogenic viruses. Fu B, et al. J Exp Med, 2017 Apr 3. PMID 28246125, Free PMC Article
  2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde transport, endosome to Golgi IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
vesicle transport protein GOT1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417653.1 → NP_001404582.1  vesicle transport protein GOT1B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC142413

  2. NM_001417654.1 → NP_001404583.1  vesicle transport protein GOT1B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC142413

  3. NM_001417655.1 → NP_001404584.1  vesicle transport protein GOT1B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC142413

  4. NM_025872.5 → NP_080148.1  vesicle transport protein GOT1B isoform 3

    See identical proteins and their annotated locations for NP_080148.1

    Status: VALIDATED

    Source sequence(s)
    AC142413
    Consensus CDS
    CCDS20682.1
    UniProtKB/Swiss-Prot
    Q9CR60
    Related
    ENSMUSP00000032372.7, ENSMUST00000032372.7
    Conserved Domains (1) summary
    cl02130
    Location:4 → 120
    Got1; Got1/Sft2-like family

RNA

  1. NR_184553.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC142413

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    142332929..142349584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152265.1 → XP_036008158.1  vesicle transport protein GOT1B isoform X1

    Conserved Domains (1) summary
    cl02130
    Location:4 → 120
    Got1; Got1/Sft2-like family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CR60.1 GenPept UniProtKB/Swiss-Prot:Q9CR60

Gene LinkOut

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