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Tbc1d19 TBC1 domain family, member 19 [ Mus musculus (house mouse) ]

Gene ID: 67249, updated on 2-Nov-2024

Summary

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Official Symbol
Tbc1d19provided by MGI
Official Full Name
TBC1 domain family, member 19provided by MGI
Primary source
MGI:MGI:1914499
See related
Ensembl:ENSMUSG00000039178 AllianceGenome:MGI:1914499
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810453K03Rik
Summary
Is expressed in nervous system. Orthologous to human TBC1D19 (TBC1 domain family member 19). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 7.7), whole brain E14.5 (RPKM 6.4) and 22 other tissues See more
Orthologs
human all
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Genomic context

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See Tbc1d19 in Genome Data Viewer
Location:
5 C1; 5 29.65 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (53966885..54066563)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (53809543..53909221)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13086 Neighboring gene STARR-seq mESC enhancer starr_13089 Neighboring gene STARR-seq mESC enhancer starr_13090 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:53980216-53980325 Neighboring gene recombination signal binding protein for immunoglobulin kappa J region Neighboring gene STARR-seq mESC enhancer starr_13092 Neighboring gene STARR-seq mESC enhancer starr_13095 Neighboring gene cholecystokinin A receptor Neighboring gene STARR-seq mESC enhancer starr_13097 Neighboring gene predicted gene, 40305 Neighboring gene predicted gene, 30601

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
TBC1 domain family member 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144517.4 → NP_653100.1  TBC1 domain family member 19

    See identical proteins and their annotated locations for NP_653100.1

    Status: VALIDATED

    Source sequence(s)
    AK076128, AK083084, BY127335, CK627425
    Consensus CDS
    CCDS19294.1
    UniProtKB/TrEMBL
    Q8VDV7
    Related
    ENSMUSP00000040585.7, ENSMUST00000037337.10
    Conserved Domains (1) summary
    smart00164
    Location:248 → 466
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    53966885..54066563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165432.1 → XP_036021325.1  TBC1 domain family member 19 isoform X1

    Conserved Domains (1) summary
    cl02495
    Location:277 → 495
    RabGAP-TBC; Rab-GTPase-TBC domain

  2. XM_006504065.4 → XP_006504128.1  TBC1 domain family member 19 isoform X2

    Conserved Domains (1) summary
    smart00164
    Location:155 → 373
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

  3. XM_030254772.1 → XP_030110632.1  TBC1 domain family member 19 isoform X2

    Conserved Domains (1) summary
    smart00164
    Location:155 → 373
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

  4. XM_006504067.4 → XP_006504130.1  TBC1 domain family member 19 isoform X4

    Conserved Domains (1) summary
    smart00164
    Location:79 → 297
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

  5. XM_017321077.1 → XP_017176566.1  TBC1 domain family member 19 isoform X4

    Conserved Domains (1) summary
    smart00164
    Location:79 → 297
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

  6. XM_036165433.1 → XP_036021326.1  TBC1 domain family member 19 isoform X3

    Conserved Domains (1) summary
    cl02495
    Location:118 → 336
    RabGAP-TBC; Rab-GTPase-TBC domain

RNA

  1. XR_004942551.1 RNA Sequence

  2. XR_004942552.1 RNA Sequence

  3. XR_003955697.2 RNA Sequence

    Related
    ENSMUST00000201958.4
Nucleotide Protein Strain
Heading Accession and Version

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