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Kirrel3 kirre like nephrin family adhesion molecule 3 [ Mus musculus (house mouse) ]

Gene ID: 67703, updated on 2-Nov-2024

Summary

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Official Symbol
Kirrel3provided by MGI
Official Full Name
kirre like nephrin family adhesion molecule 3provided by MGI
Primary source
MGI:MGI:1914953
See related
Ensembl:ENSMUSG00000032036 AllianceGenome:MGI:1914953
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SST4; NEPH2; mKIAA1867; 1500010O20Rik; 2900036G11Rik
Summary
Predicted to enable cell adhesion molecule binding activity. Involved in hemopoiesis; homophilic cell adhesion via plasma membrane adhesion molecules; and nervous system development. Acts upstream of or within glomerulus morphogenesis; inter-male aggressive behavior; and nervous system development. Located in several cellular components, including axon; dendritic shaft; and extracellular region. Is expressed in several structures, including Rathke's pouch; branchial arch; central nervous system; limb bud; and sensory organ. Orthologous to human KIRREL3 (kirre like nephrin family adhesion molecule 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in cerebellum adult (RPKM 9.9), frontal lobe adult (RPKM 5.7) and 7 other tissues See more
Orthologs
human all
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Genomic context

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See Kirrel3 in Genome Data Viewer
Location:
9 A4; 9 18.97 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (34396850..34952103)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (34485853..35040807)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 7630403G23 gene Neighboring gene predicted gene, 32359 Neighboring gene STARR-seq mESC enhancer starr_23752 Neighboring gene STARR-seq mESC enhancer starr_23754 Neighboring gene predicted gene, 33777 Neighboring gene predicted gene, 33561 Neighboring gene kirre like nephrin family adhesion molecule 3, opposite strand Neighboring gene STARR-positive B cell enhancer ABC_E3822 Neighboring gene STARR-seq mESC enhancer starr_23759 Neighboring gene RIKEN cDNA 4930581F22 gene Neighboring gene STARR-seq mESC enhancer starr_23763 Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 4 Neighboring gene predicted gene, 51705 Neighboring gene predicted gene, 57537

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mice lacking the synaptic adhesion molecule Neph2/Kirrel3 display moderate hyperactivity and defective novel object preference. Choi SY, et al. Front Cell Neurosci, 2015. PMID 26283919, Free PMC Article
  2. Comprehensive expression pattern of kin of irregular chiasm-like 3 in the adult mouse brain. Hisaoka T, et al. Biochem Biophys Res Commun, 2021 Jul 23. PMID 34062388
  3. Kirrel3-Mediated Synapse Formation Is Attenuated by Disease-Associated Missense Variants. Taylor MR, et al. J Neurosci, 2020 Jul 8. PMID 32503885, Free PMC Article
  4. Increased Excitatory Synaptic Transmission of Dentate Granule Neurons in Mice Lacking PSD-95-Interacting Adhesion Molecule Neph2/Kirrel3 during the Early Postnatal Period. Roh JD, et al. Front Mol Neurosci, 2017. PMID 28381988, Free PMC Article
  5. Adhesion molecule Kirrel3/Neph2 is required for the elongated shape of myocytes during skeletal muscle differentiation. Tamir-Livne Y, et al. Int J Dev Biol, 2017. PMID 28621431

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
    Title: Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
  2. Comprehensive expression pattern of kin of irregular chiasm-like 3 in the adult mouse brain.
    Title: Comprehensive expression pattern of kin of irregular chiasm-like 3 in the adult mouse brain.
  3. Kirrel3-Mediated Synapse Formation Is Attenuated by Disease-Associated Missense Variants.
    Title: Kirrel3-Mediated Synapse Formation Is Attenuated by Disease-Associated Missense Variants.
  4. Kirrel2 is required for axonal coalescence in subsets of Olfactory sensory neurons that project axons to the DII (dorsal) region; Kirrel2/3-independent mechanisms also control olfactory sensory neurons axonal coalescence in certain regions of the Olfactory bulb.
    Title: Kirrel2 is differentially required in populations of olfactory sensory neurons for the targeting of axons in the olfactory bulb.
  5. The results of this study demonstrate that Kirrel2 and Kirrel3 are essential for the formation of glomeruli and suggest they contribute to synaptogenesis in the accessory olfactory bulb.
    Title: Loss of Kirrel family members alters glomerular structure and synapse numbers in the accessory olfactory bulb.
  6. Findings provide evidence that Kirrel3(-/-) mice exhibit autistic-like behaviors, including social and communicative deficits, repetitive behaviors, and sensory abnormalities, as well as hyperactivity.
    Title: Abnormal behaviours relevant to neurodevelopmental disorders in Kirrel3-knockout mice.
  7. This study demonstrated that selective loss of mossy fiber filopodial synapses with GABA neurons likely underlies the hippocampal activity imbalance observed in Kirrel3 knockout mice and may impact neural function in patients with Kirrel3-dependent neurodevelopmental disorders.
    Title: Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice.
  8. mouse Kirrel3 is a myobast adhesion molecule which promotes the morphological change of rounded MPC to a spindle shaped myocyte that migrates in a directed fashion and participates in the tight interactions between myocytes prior to their fusion
    Title: Adhesion molecule Kirrel3/Neph2 is required for the elongated shape of myocytes during skeletal muscle differentiation.
  9. Kirrel3 is required for formation of hippocampal mossy fiber filopodia; the structures that give rise to dentate granule-GABA synapses and that regulate feed-forward inhibition of CA3 neurons.
    Title: The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus.
  10. Kirrel3 has a role in coalescence of vomeronasal sensory neuron axons into glomeruli and in male-male aggression in a resident-intruder assay
    Title: Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression.
Submit: New GeneRIF Correction See all GeneRIFs (17)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables PDZ domain binding NAS
Non-traceable Author Statement
more info
 PubMed 
enables cell adhesion molecule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glomerulus morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in hemopoiesis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in hippocampus development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within inter-male aggressive behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neuron migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neuron projection morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within principal sensory nucleus of trigeminal nerve development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synapse assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synapse assembly IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell-cell junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendritic shaft IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
kin of IRRE-like protein 3
Names
X kin of IRRE like 3
kin of IRRE like 3
kin of irregular chiasm-like protein 3
membrane protein mKirre
nephrin-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190911.2 → NP_001177840.1  kin of IRRE-like protein 3 isoform A precursor

    See identical proteins and their annotated locations for NP_001177840.1

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639
    UniProtKB/Swiss-Prot
    Q6P555, Q810H3, Q8BGQ5, Q8BR86, Q8BRS8
    Conserved Domains (4) summary
    cd00096
    Location:343 → 347
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:149 → 246
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:418 → 515
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  2. NM_001190912.2 → NP_001177841.1  kin of IRRE-like protein 3 isoform C precursor

    See identical proteins and their annotated locations for NP_001177841.1

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639
    Consensus CDS
    CCDS80973.1
    UniProtKB/TrEMBL
    Q3TAG1
    Related
    ENSMUSP00000140219.2, ENSMUST00000187182.7
    Conserved Domains (4) summary
    cd05759
    Location:139 → 220
    Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
    cd05898
    Location:392 → 489
    Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)
    smart00409
    Location:28 → 117
    IG; Immunoglobulin
    cl11960
    Location:309 → 390
    Ig; Immunoglobulin domain

  3. NM_001190913.2 → NP_001177842.1  kin of IRRE-like protein 3 isoform D precursor

    See identical proteins and their annotated locations for NP_001177842.1

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639
    UniProtKB/TrEMBL
    A0A087WPC0
    Related
    ENSMUSP00000139714.2, ENSMUST00000190549.7
    Conserved Domains (7) summary
    cd05759
    Location:165 → 246
    Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
    cd05898
    Location:418 → 515
    Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)
    smart00408
    Location:349 → 400
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:426 → 515
    IG_like; Immunoglobulin like
    pfam07679
    Location:335 → 416
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:254 → 318
    Ig_3; Immunoglobulin domain
    cl11960
    Location:52 → 143
    Ig; Immunoglobulin domain

  4. NM_001190914.2 → NP_001177843.1  kin of IRRE-like protein 3 isoform E

    See identical proteins and their annotated locations for NP_001177843.1

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639
    Consensus CDS
    CCDS57667.1
    UniProtKB/TrEMBL
    G5E8B6, Q3TAG1
    Related
    ENSMUSP00000048863.7, ENSMUST00000045091.13
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  5. NM_001433785.1 → NP_001420714.1  kin of IRRE-like protein 3 isoform F precursor

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639

  6. NM_001433786.1 → NP_001420715.1  kin of IRRE-like protein 3 isoform G precursor

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639

  7. NM_001433787.1 → NP_001420716.1  kin of IRRE-like protein 3 isoform H precursor

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639

  8. NM_001433788.1 → NP_001420717.1  kin of IRRE-like protein 3 isoform I

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639, AC156641

  9. NM_001433789.1 → NP_001420718.1  kin of IRRE-like protein 3 isoform J

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639, AC156641

  10. NM_001433790.1 → NP_001420719.1  kin of IRRE-like protein 3 isoform K precursor

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639

  11. NM_001433791.1 → NP_001420720.1  kin of IRRE-like protein 3 isoform L precursor

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639

  12. NM_001433792.1 → NP_001420721.1  kin of IRRE-like protein 3 isoform M precursor

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639

  13. NM_026324.4 → NP_080600.1  kin of IRRE-like protein 3 isoform B precursor

    See identical proteins and their annotated locations for NP_080600.1

    Status: VALIDATED

    Source sequence(s)
    AC155250, AC156639
    Consensus CDS
    CCDS40574.1
    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (4) summary
    cd05759
    Location:165 → 246
    Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
    cd05898
    Location:418 → 515
    Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)
    smart00410
    Location:54 → 143
    IG_like; Immunoglobulin like
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    34396850..34952103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155204.1 → XP_036011097.1  kin of IRRE-like protein 3 isoform X1

    Conserved Domains (5) summary
    smart00410
    Location:54 → 143
    IG_like; Immunoglobulin like
    cd00096
    Location:343 → 347
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:149 → 246
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:418 → 515
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  2. XM_006510557.5 → XP_006510620.1  kin of IRRE-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006510620.1

    Conserved Domains (5) summary
    smart00410
    Location:54 → 143
    IG_like; Immunoglobulin like
    cd00096
    Location:343 → 347
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:149 → 246
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:418 → 515
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  3. XM_006510560.5 → XP_006510623.1  kin of IRRE-like protein 3 isoform X3

    See identical proteins and their annotated locations for XP_006510623.1

    UniProtKB/Swiss-Prot
    Q6P555, Q810H3, Q8BGQ5, Q8BR86, Q8BRS8
    Conserved Domains (4) summary
    cd00096
    Location:343 → 347
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:149 → 246
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:418 → 515
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  4. XM_006510559.5 → XP_006510622.1  kin of IRRE-like protein 3 isoform X2

    Conserved Domains (4) summary
    cd05759
    Location:165 → 246
    Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
    cd05898
    Location:418 → 515
    Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)
    smart00409
    Location:54 → 143
    IG; Immunoglobulin
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  5. XM_006510563.5 → XP_006510626.1  kin of IRRE-like protein 3 isoform X6

    See identical proteins and their annotated locations for XP_006510626.1

    UniProtKB/TrEMBL
    Q3TAG1
    Related
    ENSMUSP00000110801.3, ENSMUST00000115148.9
    Conserved Domains (4) summary
    cd05759
    Location:165 → 246
    Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
    cd05898
    Location:418 → 515
    Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)
    smart00410
    Location:54 → 143
    IG_like; Immunoglobulin like
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  6. XM_006510558.5 → XP_006510621.1  kin of IRRE-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006510621.1

    Conserved Domains (5) summary
    smart00410
    Location:54 → 143
    IG_like; Immunoglobulin like
    cd00096
    Location:343 → 347
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:149 → 246
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:418 → 515
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  7. XM_036155205.1 → XP_036011098.1  kin of IRRE-like protein 3 isoform X3

    UniProtKB/Swiss-Prot
    Q6P555, Q810H3, Q8BGQ5, Q8BR86, Q8BRS8
    Conserved Domains (4) summary
    cd00096
    Location:343 → 347
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:149 → 246
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:418 → 515
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:335 → 416
    Ig; Immunoglobulin domain

  8. XM_006510561.5 → XP_006510624.1  kin of IRRE-like protein 3 isoform X4

    See identical proteins and their annotated locations for XP_006510624.1

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (4) summary
    cd05759
    Location:139 → 220
    Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
    cd05898
    Location:392 → 489
    Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)
    smart00409
    Location:28 → 117
    IG; Immunoglobulin
    cl11960
    Location:309 → 390
    Ig; Immunoglobulin domain

  9. XM_036155207.1 → XP_036011100.1  kin of IRRE-like protein 3 isoform X5

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  10. XM_036155211.1 → XP_036011104.1  kin of IRRE-like protein 3 isoform X7

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:28 → 117
    IG_like; Immunoglobulin like
    cd00096
    Location:317 → 321
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:123 → 220
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:392 → 489
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:309 → 390
    Ig; Immunoglobulin domain

  11. XM_036155206.1 → XP_036011099.1  kin of IRRE-like protein 3 isoform X5

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  12. XM_036155208.1 → XP_036011101.1  kin of IRRE-like protein 3 isoform X5

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  13. XM_036155213.1 → XP_036011106.1  kin of IRRE-like protein 3 isoform X9

    UniProtKB/TrEMBL
    G5E8B6, Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  14. XM_036155210.1 → XP_036011103.1  kin of IRRE-like protein 3 isoform X5

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  15. XM_030244529.2 → XP_030100389.1  kin of IRRE-like protein 3 isoform X8

    UniProtKB/TrEMBL
    A0A087WNM9, Q3TAG1
    Related
    ENSMUSP00000139418.2, ENSMUST00000188933.7
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  16. XM_036155214.1 → XP_036011107.1  kin of IRRE-like protein 3 isoform X9

    UniProtKB/TrEMBL
    G5E8B6, Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  17. XM_036155209.1 → XP_036011102.1  kin of IRRE-like protein 3 isoform X5

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  18. XM_017313538.3 → XP_017169027.1  kin of IRRE-like protein 3 isoform X5

    UniProtKB/TrEMBL
    Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  19. XM_017313539.3 → XP_017169028.1  kin of IRRE-like protein 3 isoform X9

    UniProtKB/TrEMBL
    G5E8B6, Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain

  20. XM_036155212.1 → XP_036011105.1  kin of IRRE-like protein 3 isoform X8

    UniProtKB/TrEMBL
    A0A087WNM9, Q3TAG1
    Conserved Domains (5) summary
    smart00410
    Location:21 → 110
    IG_like; Immunoglobulin like
    cd00096
    Location:310 → 314
    Ig; Ig strand A' [structural motif]
    cd05759
    Location:116 → 213
    IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05898
    Location:385 → 482
    IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:302 → 383
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BR86.1 GenPept UniProtKB/Swiss-Prot:Q8BR86

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