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Meig1 meiosis/spermiogenesis associated 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 679834, updated on 2-Nov-2024

Summary

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Official Symbol
Meig1provided by RGD
Official Full Name
meiosis/spermiogenesis associated 1provided by RGD
Primary source
RGD:1583655
See related
EnsemblRapid:ENSRNOG00000016283 AllianceGenome:RGD:1583655
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within manchette assembly and protein localization. Predicted to be located in cytosol and manchette. Predicted to be active in nucleus. Orthologous to human MEIG1 (meiosis/spermiogenesis associated 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 809.2) See more
Orthologs
human mouse all
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Genomic context

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See Meig1 in Genome Data Viewer
Location:
17q12.3
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (79718630..79737604)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (74810791..74828433)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (78813656..78829411)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097881 Neighboring gene SUV39H2 histone lysine methyltransferase Neighboring gene DNA cross-link repair 1C Neighboring gene metallothionein 1, pseudogene 3 Neighboring gene uncharacterized LOC120097878 Neighboring gene ribosomal protein L34, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis. Zhang Z, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15328412, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within manchette assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within protein localization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of sperm axoneme assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within sperm axoneme assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in manchette ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
meiosis expressed gene 1 protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134882.1 → NP_001128354.1  meiosis expressed gene 1 protein homolog

    See identical proteins and their annotated locations for NP_001128354.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    79718630..79737604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063276729.1 → XP_063132799.1  meiosis expressed gene 1 protein homolog isoform X1

    UniProtKB/TrEMBL
    A6JM18, D4A0V5

  2. XM_006254278.5 → XP_006254340.1  meiosis expressed gene 1 protein homolog isoform X1

    See identical proteins and their annotated locations for XP_006254340.1

    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed

  3. XM_017600662.3 → XP_017456151.1  meiosis expressed gene 1 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed

  4. XM_008771888.4 → XP_008770110.1  meiosis expressed gene 1 protein homolog isoform X1

    See identical proteins and their annotated locations for XP_008770110.1

    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed

  5. XM_006254276.4 → XP_006254338.1  meiosis expressed gene 1 protein homolog isoform X1

    See identical proteins and their annotated locations for XP_006254338.1

    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed

  6. XM_039096057.1 → XP_038951985.1  meiosis expressed gene 1 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Related
    ENSRNOP00000069398.2, ENSRNOT00000090779.3
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed

  7. XM_039096058.2 → XP_038951986.1  meiosis expressed gene 1 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A0G2JV95, A6JM18, D4A0V5
    Conserved Domains (1) summary
    pfam15163
    Location:11 → 86
    Meiosis_expr; Meiosis-expressed
Nucleotide Protein Strain
Heading Accession and Version

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