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Tomm5 translocase of outer mitochondrial membrane 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 680080, updated on 2-Nov-2024

Summary

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Official Symbol
Tomm5provided by RGD
Official Full Name
translocase of outer mitochondrial membrane 5provided by RGD
Primary source
RGD:1596808
See related
AllianceGenome:RGD:1596808
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in protein targeting to mitochondrion and protein transport. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial outer membrane translocase complex. Orthologous to human TOMM5 (translocase of outer mitochondrial membrane 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 451.8), Muscle (RPKM 325.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tomm5 in Genome Data Viewer
Location:
5q22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (64158026..64160857, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (59362360..59365191, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (60655708..60658568, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene RNA polymerase I subunit E Neighboring gene F-box protein 10 Neighboring gene ribosomal protein L24-like Neighboring gene uncharacterized LOC120103148

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Biogenesis of mitochondrial outer membrane proteins, problems and diseases. Ellenrieder L, et al. Biol Chem, 2015 Nov. PMID 25980382
  2. Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane. Kato H, et al. Biochem Biophys Res Commun, 2008 May 9. PMID 18331822
  3. Cooperation of protein machineries in mitochondrial protein sorting. Wenz LS, et al. Biochim Biophys Acta, 2015 May. PMID 25633533
  4. Assembly of β-barrel proteins in the mitochondrial outer membrane. Höhr AI, et al. Biochim Biophys Acta, 2015 Jan. PMID 25305573
  5. Unlocking the presequence import pathway. Schulz C, et al. Trends Cell Biol, 2015 May. PMID 25542066

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein targeting to mitochondrion IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial outer membrane translocase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial outer membrane translocase complex ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
mitochondrial import receptor subunit TOM5 homolog
Names
translocase of outer mitochondrial membrane 5 homolog
translocase of outer mitochondrial membrane 5 homolog-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398960.1 → NP_001385889.1  mitochondrial import receptor subunit TOM5 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6IJ86
    Conserved Domains (1) summary
    pfam10642
    Location:1 → 50
    Tom5; Mitochondrial import receptor subunit or translocase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    64158026..64160857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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