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Llcfc1 LLLL and CFNLAS motif containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 680112, updated on 2-Nov-2024

Summary

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Official Symbol
Llcfc1provided by RGD
Official Full Name
LLLL and CFNLAS motif containing 1provided by RGD
Primary source
RGD:1595510
See related
EnsemblRapid:ENSRNOG00000025618 AllianceGenome:RGD:1595510
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization. Orthologous to human LLCFC1 (LLLL and CFNLAS motif containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 340.3) See more
Orthologs
human mouse all
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Genomic context

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See Llcfc1 in Genome Data Viewer
Location:
4q23
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (71532854..71534229)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (70566206..70567592)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (70977476..70978855)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel, subfamily V, member 6 Neighboring gene transient receptor potential cation channel, subfamily V, member 5 Neighboring gene Kell metallo-endopeptidase (Kell blood group) Neighboring gene NADH:ubiquinone oxidoreductase subunit A2, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in fusion of sperm to egg plasma membrane involved in single fertilization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fusion of sperm to egg plasma membrane involved in single fertilization ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
sperm-egg fusion protein LLCFC1
Names
uncharacterized protein C7orf34 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109392.1 → NP_001102862.1  sperm-egg fusion protein LLCFC1 precursor

    See identical proteins and their annotated locations for NP_001102862.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473959
    UniProtKB/TrEMBL
    A6IF49, D4A4Y5
    Related
    ENSRNOP00000030740.2, ENSRNOT00000031984.4
    Conserved Domains (1) summary
    pfam15838
    Location:35 → 105
    DUF4717; Domain of unknown function (DUF4717)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    71532854..71534229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006236383.5 → XP_006236445.1  sperm-egg fusion protein LLCFC1 isoform X1

    Related
    ENSRNOP00000099356.1, ENSRNOT00000148248.1
    Conserved Domains (1) summary
    pfam15838
    Location:40 → 110
    DUF4717; Domain of unknown function (DUF4717)
Nucleotide Protein Strain
Heading Accession and Version

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