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Ccdc74a coiled-coil domain containing 74A [ Rattus norvegicus (Norway rat) ]

Gene ID: 680752, updated on 2-Nov-2024

Summary

Official Symbol
Ccdc74aprovided by RGD
Official Full Name
coiled-coil domain containing 74Aprovided by RGD
Primary source
RGD:1588214
See related
EnsemblRapid:ENSRNOG00000001876 AllianceGenome:RGD:1588214
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to several human genes including CCDC74A (coiled-coil domain containing 74A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 37.2), Testes (RPKM 32.6) and 9 other tissues See more
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Genomic context

See Ccdc74a in Genome Data Viewer
Location:
11q23
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (96860161..96864540, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (83355888..83360269, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (87547026..87554513)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15, pseudogene 13 Neighboring gene mediator complex subunit 15 Neighboring gene ribosomal protein L34, pseudogene 2 Neighboring gene U6 spliceosomal RNA Neighboring gene sphingomyelin phosphodiesterase 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
coiled-coil domain-containing protein 74B
Names
coiled-coil domain-containing protein 74A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419901.1NP_001406830.1  coiled-coil domain-containing protein 74B isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A6JSK6, F1M8E1
    Related
    ENSRNOP00000002567.7, ENSRNOT00000002567.8
  2. NM_001419902.1NP_001406831.1  coiled-coil domain-containing protein 74B isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    Related
    ENSRNOP00000112247.1, ENSRNOT00000151680.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    96860161..96864540 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039088987.2XP_038944915.1  coiled-coil domain-containing protein 74B isoform X2

    Conserved Domains (1) summary
    pfam14917
    Location:48165
    CCDC74_C; Coiled coil protein 74, C terminal
  2. XM_039088985.2XP_038944913.1  coiled-coil domain-containing protein 74B isoform X1

    Conserved Domains (1) summary
    pfam14917
    Location:116233
    CCDC74_C; Coiled coil protein 74, C terminal
  3. XM_063270763.1XP_063126833.1  coiled-coil domain-containing protein 74B isoform X2