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Timm8a2 translocase of inner mitochondrial membrane 8A2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 680794, updated on 10-Jul-2024

Summary

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Official Symbol
Timm8a2provided by RGD
Official Full Name
translocase of inner mitochondrial membrane 8A2provided by RGD
Primary source
RGD:1588172
See related
EnsemblRapid:ENSRNOG00000013835 AllianceGenome:RGD:1588172
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in protein transport. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in deafness-dystonia-optic neuronopathy syndrome and dystonia. Orthologous to human TIMM8A (translocase of inner mitochondrial membrane 8A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 36.6) See more
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Genomic context

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See Timm8a2 in Genome Data Viewer
Location:
15q25
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (105529725..105537745)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (99123374..99131097)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (108448351..108456834)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene UBA domain containing 2 Neighboring gene G protein-coupled receptor 183 Neighboring gene uncharacterized LOC108352982 Neighboring gene uncharacterized LOC134482164 Neighboring gene transmembrane 9 superfamily member 2 Neighboring gene FKBP prolyl isomerase 3, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
translocase of inner mitochondrial membrane 8A2
Names
translocase of inner mitochondrial membrane 8 homolog a2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109429.1 → NP_001102899.1  translocase of inner mitochondrial membrane 8A2

    See identical proteins and their annotated locations for NP_001102899.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473951
    UniProtKB/TrEMBL
    A6HUL0, D3ZV76
    Related
    ENSRNOP00000018486.3, ENSRNOT00000018486.5
    Conserved Domains (1) summary
    pfam02953
    Location:21 → 81
    zf-Tim10_DDP; Tim10/DDP family zinc finger

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    105529725..105537745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063274628.1 → XP_063130698.1  translocase of inner mitochondrial membrane 8A2 isoform X1

    UniProtKB/TrEMBL
    A6HUL0, D3ZV76

  2. XM_063274627.1 → XP_063130697.1  translocase of inner mitochondrial membrane 8A2 isoform X1

    UniProtKB/TrEMBL
    A6HUL0, D3ZV76
Nucleotide Protein Strain
Heading Accession and Version

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