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Erh ERH, mRNA splicing and mitosis factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 681415, updated on 2-Nov-2024

Summary

Official Symbol
Erhprovided by RGD
Official Full Name
ERH, mRNA splicing and mitosis factorprovided by RGD
Primary source
RGD:1595409
See related
EnsemblRapid:ENSRNOG00000004883 AllianceGenome:RGD:1595409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable methyl-CpG binding activity. Predicted to be located in midbody and nucleus. Predicted to be part of methylosome. Orthologous to human ERH (ERH mRNA splicing and mitosis factor). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 329.3), Spleen (RPKM 261.9) and 9 other tissues See more
Orthologs
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Genomic context

See Erh in Genome Data Viewer
Location:
6q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (106012255..106022521, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (100280933..100291200, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (104280390..104290905, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene exonuclease 3'-5' domain containing 2 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 16 Neighboring gene uncharacterized LOC134479446 Neighboring gene uncharacterized LOC134479447 Neighboring gene solute carrier family 39, member 9 Neighboring gene pleckstrin homology and coiled-coil domain containing D1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables methyl-CpG binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of methylosome ISO
Inferred from Sequence Orthology
more info
 
located_in midbody ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
enhancer of rudimentary homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109442.2NP_001102912.1  enhancer of rudimentary homolog isoform 1

    See identical proteins and their annotated locations for NP_001102912.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6AFK4, A0A8J8Y9X7, A6JDI9
    Related
    ENSRNOP00000059304.4, ENSRNOT00000066014.5
    Conserved Domains (1) summary
    pfam01133
    Location:22118
    ER; Enhancer of rudimentary
  2. NM_001419497.1NP_001406426.1  enhancer of rudimentary homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I5ZSD4, B2RYQ5, F1M4T3
    Related
    ENSRNOP00000081166.1, ENSRNOT00000100687.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    106012255..106022521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)