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Ap3s2 adaptor related protein complex 3 subunit sigma 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 683402, updated on 2-Nov-2024

Summary

Official Symbol
Ap3s2provided by RGD
Official Full Name
adaptor related protein complex 3 subunit sigma 2provided by RGD
Primary source
RGD:1586888
See related
EnsemblRapid:ENSRNOG00000043141 AllianceGenome:RGD:1586888
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Is active in synaptic vesicle. Orthologous to human AP3S2 (adaptor related protein complex 3 subunit sigma 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 267.6), Heart (RPKM 163.1) and 9 other tissues See more
Orthologs
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Genomic context

See Ap3s2 in Genome Data Viewer
Location:
1q31
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (143228131..143268573, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (133818825..133859269, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (141612961..141655417, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene mesoderm posterior bHLH transcription factor 2 Neighboring gene alanyl aminopeptidase, membrane Neighboring gene uncharacterized LOC134483742 Neighboring gene uncharacterized LOC120099870 Neighboring gene actin-related protein 2/3 complex inhibitor

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Golgi to vacuole transport IEA
Inferred from Electronic Annotation
more info
 
involved_in anterograde axonal transport ISO
Inferred from Sequence Orthology
more info
 
involved_in anterograde synaptic vesicle transport ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of AP-3 adaptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
is_active_in synaptic vesicle EXP
Inferred from Experiment
more info
PubMed 
is_active_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
AP-3 complex subunit sigma-2
Names
adaptor-related protein complex 3, sigma 2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001115039.1NP_001108511.1  AP-3 complex subunit sigma-2

    See identical proteins and their annotated locations for NP_001108511.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158881
    UniProtKB/TrEMBL
    B0BNM6, F1LVM4
    Related
    ENSRNOP00000088313.1, ENSRNOT00000096941.2
    Conserved Domains (1) summary
    cd14834
    Location:1146
    AP3_sigma; AP-3 complex subunit sigma

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    143228131..143268573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)