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Cryga crystallin, gamma A [ Rattus norvegicus (Norway rat) ]

Gene ID: 684028, updated on 2-Nov-2024

Summary

Symbol
Crygaprovided by RGD
Full Name
crystallin, gamma Aprovided by RGD
Primary source
RGD:1595217
See related
EnsemblRapid:ENSRNOG00000046343 AllianceGenome:RGD:1595217
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of eye lens. Involved in lens development in camera-type eye. Orthologous to human CRYGA (crystallin gamma A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 34.6), Brain (RPKM 18.9) and 1 other tissue See more
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Genomic context

See Cryga in Genome Data Viewer
Location:
9q32
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (73975914..74006614, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (66482176..66484638, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (71828308..71855900, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene crystallin, gamma C Neighboring gene crystallin, gamma B Neighboring gene transfer RNA proline (anticodon AGG) 73 Neighboring gene isocitrate dehydrogenase (NADP(+)) 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within eye development ISO
Inferred from Sequence Orthology
more info
 
involved_in lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in lens development in camera-type eye IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within lens development in camera-type eye ISO
Inferred from Sequence Orthology
more info
 
involved_in visual perception IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
gamma-crystallin A
Names
CRY-gamma-A
gamma-A-crystallin
gamma-crystallin 1-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080936.2NP_001074405.1  gamma-crystallin A

    See identical proteins and their annotated locations for NP_001074405.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    P10065
    Related
    ENSRNOP00000019963.3, ENSRNOT00000019963.5
    Conserved Domains (2) summary
    smart00247
    Location:382
    XTALbg; Beta/gamma crystallins
    pfam00030
    Location:89170
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    73975914..74006614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063267734.1XP_063123804.1  gamma-crystallin A isoform X2

    Related
    ENSRNOP00000107573.1, ENSRNOT00000146939.1
  2. XM_063267735.1XP_063123805.1  gamma-crystallin A isoform X3

  3. XM_063267733.1XP_063123803.1  gamma-crystallin A isoform X1

    UniProtKB/TrEMBL
    A6IPJ4, M0R5G4
    Related
    ENSRNOP00000064629.3, ENSRNOT00000072983.4
  4. XM_063267736.1XP_063123806.1  gamma-crystallin A isoform X4

  5. XM_063267737.1XP_063123807.1  gamma-crystallin A isoform X4

  6. XM_063267738.1XP_063123808.1  gamma-crystallin A isoform X5

RNA

  1. XR_010054633.1 RNA Sequence