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Zfpl1 zinc finger protein-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 684755, updated on 2-Nov-2024

Summary

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Official Symbol
Zfpl1provided by RGD
Official Full Name
zinc finger protein-like 1provided by RGD
Primary source
RGD:1586738
See related
EnsemblRapid:ENSRNOG00000050180 AllianceGenome:RGD:1586738
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human ZFPL1 (zinc finger protein like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 73.4), Lung (RPKM 70.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfpl1 in Genome Data Viewer
Location:
1q43
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212803790..212807803, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203374500..203378518, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221444588..221448555, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene VPS51 subunit of GARP complex Neighboring gene microRNA 6315 Neighboring gene transmembrane protein 262 Neighboring gene cell division cycle associated 5 Neighboring gene N-acetylated alpha-linked acidic dipeptidase-like 1 Neighboring gene SAC3 domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. ZFPL1, a novel ring finger protein required for cis-Golgi integrity and efficient ER-to-Golgi transport. Chiu CF, et al. EMBO J, 2008 Apr 9. PMID 18323775, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286936.1 → NP_001273865.1  zinc finger protein-like 1

    See identical proteins and their annotated locations for NP_001273865.1

    Status: VALIDATED

    Source sequence(s)
    BU758664, CB717504, DY546174
    UniProtKB/TrEMBL
    A6HZD4, M0RCA3
    Conserved Domains (1) summary
    cd16487
    Location:50 → 104
    mRING-H2-C3DHC3_ZFPL1; Modified RING finger, H2 subclass (C3DHC3-type), found in zinc finger protein-like 1 (ZFPL1) and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    212803790..212807803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230901.5 → XP_006230963.1  zinc finger protein-like 1 isoform X1

    See identical proteins and their annotated locations for XP_006230963.1

    UniProtKB/TrEMBL
    A6HZD4, M0RCA3
    Conserved Domains (1) summary
    cd16487
    Location:50 → 104
    mRING-H2-C3DHC3_ZFPL1; Modified RING finger, H2 subclass (C3DHC3-type), found in zinc finger protein-like 1 (ZFPL1) and similar proteins

  2. XM_008760175.3 → XP_008758397.1  zinc finger protein-like 1 isoform X1

    See identical proteins and their annotated locations for XP_008758397.1

    UniProtKB/TrEMBL
    A6HZD4, M0RCA3
    Related
    ENSRNOP00000067214.1, ENSRNOT00000075165.4
    Conserved Domains (1) summary
    cd16487
    Location:50 → 104
    mRING-H2-C3DHC3_ZFPL1; Modified RING finger, H2 subclass (C3DHC3-type), found in zinc finger protein-like 1 (ZFPL1) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

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