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Myadml2 myeloid-associated differentiation marker-like 2 [ Mus musculus (house mouse) ]

Gene ID: 68515, updated on 28-Oct-2024

Summary

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Official Symbol
Myadml2provided by MGI
Official Full Name
myeloid-associated differentiation marker-like 2provided by MGI
Primary source
MGI:MGI:1915765
See related
Ensembl:ENSMUSG00000025141 AllianceGenome:MGI:1915765
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110012N22Rik
Summary
Predicted to be located in cytoplasm. Orthologous to human MYADML2 (myeloid associated differentiation marker like 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in heart adult (RPKM 23.9), mammary gland adult (RPKM 7.7) and 3 other tissues See more
Orthologs
human all
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Genomic context

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See Myadml2 in Genome Data Viewer
Location:
11 E2; 11 84.37 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120536857..120539188, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (120646031..120648337, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7115 Neighboring gene v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) Neighboring gene predicted gene, 17586 Neighboring gene STARR-positive B cell enhancer mm9_chr11:120504984-120505285 Neighboring gene pyrroline-5-carboxylate reductase 1 Neighboring gene notum palmitoleoyl-protein carboxylesterase Neighboring gene STARR-seq mESC enhancer starr_31365 Neighboring gene ASPSCR1 tether for SLC2A4, UBX domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC107698

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
myeloid-associated differentiation marker-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204820.1 → NP_001191749.1  myeloid-associated differentiation marker-like protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001191749.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK003645, AL663030, BC091000
    Consensus CDS
    CCDS56828.1
    UniProtKB/Swiss-Prot
    Q08AU7
    Related
    ENSMUSP00000026134.3, ENSMUST00000026134.3
    Conserved Domains (1) summary
    pfam01284
    Location:17 → 115
    MARVEL; Membrane-associating domain

  2. NM_026751.1 → NP_081027.1  myeloid-associated differentiation marker-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_081027.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL663030, BC091000, BC109329, BY636421
    Consensus CDS
    CCDS88298.1
    UniProtKB/Swiss-Prot
    Q08AU7, Q5BKP1, Q9D1F1
    Related
    ENSMUSP00000158986.2, ENSMUST00000239158.2
    Conserved Domains (1) summary
    pfam01284
    Location:159 → 297
    MARVEL; Membrane-associating domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    120536857..120539188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017314729.3 → XP_017170218.1  myeloid-associated differentiation marker-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q08AU7, Q5BKP1, Q9D1F1
    Conserved Domains (1) summary
    pfam01284
    Location:159 → 297
    MARVEL; Membrane-associating domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08AU7.2 GenPept UniProtKB/Swiss-Prot:Q08AU7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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