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Zc3h10 zinc finger CCCH type containing 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685928, updated on 2-Nov-2024

Summary

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Official Symbol
Zc3h10provided by RGD
Official Full Name
zinc finger CCCH type containing 10provided by RGD
Primary source
RGD:1587846
See related
EnsemblRapid:ENSRNOG00000040281 AllianceGenome:RGD:1587846
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable miRNA binding activity. Predicted to be involved in negative regulation of miRNA processing and regulation of RNA splicing. Predicted to act upstream of with a positive effect on post-transcriptional regulation of gene expression. Predicted to be located in nucleus. Orthologous to human ZC3H10 (zinc finger CCCH-type containing 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 46.7), Thymus (RPKM 41.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zc3h10 in Genome Data Viewer
Location:
7q11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (1557948..1562129, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (973415..977742, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (2968428..2972521, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene extended synaptotagmin 1 Neighboring gene ribosomal protein S23, pseudogene 3 Neighboring gene ribosomal protein S15, pseudogene 2 Neighboring gene ribosomal protein L41 Neighboring gene proliferation-associated 2G4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis. Treiber T, et al. Mol Cell, 2017 Apr 20. PMID 28431233
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables miRNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of miRNA processing ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_positive_effect post-transcriptional regulation of gene expression ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger CCCH domain-containing protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191090.1 → NP_001178019.1  zinc finger CCCH domain-containing protein 10

    See identical proteins and their annotated locations for NP_001178019.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A6KSE9, D3ZLM7
    Related
    ENSRNOP00000090698.1, ENSRNOT00000106284.2
    Conserved Domains (3) summary
    smart00356
    Location:40 → 62
    ZnF_C3H1; zinc finger
    pfam06005
    Location:243 → 279
    ZapB; Cell division protein ZapB
    pfam18345
    Location:140 → 158
    zf_CCCH_4; Zinc finger domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    1557948..1562129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079910.2 → XP_038935838.1  zinc finger CCCH domain-containing protein 10 isoform X1

    UniProtKB/TrEMBL
    A6KSE9, D3ZLM7
    Conserved Domains (3) summary
    smart00356
    Location:40 → 62
    ZnF_C3H1; zinc finger
    pfam06005
    Location:243 → 279
    ZapB; Cell division protein ZapB
    pfam18345
    Location:140 → 158
    zf_CCCH_4; Zinc finger domain

  2. XM_039079909.2 → XP_038935837.1  zinc finger CCCH domain-containing protein 10 isoform X1

    UniProtKB/TrEMBL
    A6KSE9, D3ZLM7
    Conserved Domains (3) summary
    smart00356
    Location:40 → 62
    ZnF_C3H1; zinc finger
    pfam06005
    Location:243 → 279
    ZapB; Cell division protein ZapB
    pfam18345
    Location:140 → 158
    zf_CCCH_4; Zinc finger domain

  3. XM_008765041.4 → XP_008763263.1  zinc finger CCCH domain-containing protein 10 isoform X1

    See identical proteins and their annotated locations for XP_008763263.1

    UniProtKB/TrEMBL
    A6KSE9, D3ZLM7
    Related
    ENSRNOP00000105235.1, ENSRNOT00000142689.1
    Conserved Domains (3) summary
    smart00356
    Location:40 → 62
    ZnF_C3H1; zinc finger
    pfam06005
    Location:243 → 279
    ZapB; Cell division protein ZapB
    pfam18345
    Location:140 → 158
    zf_CCCH_4; Zinc finger domain

  4. XM_017595116.3 → XP_017450605.1  zinc finger CCCH domain-containing protein 10 isoform X1

    UniProtKB/TrEMBL
    A6KSE9, D3ZLM7
    Related
    ENSRNOP00000058705.2, ENSRNOT00000061995.5
    Conserved Domains (3) summary
    smart00356
    Location:40 → 62
    ZnF_C3H1; zinc finger
    pfam06005
    Location:243 → 279
    ZapB; Cell division protein ZapB
    pfam18345
    Location:140 → 158
    zf_CCCH_4; Zinc finger domain
Nucleotide Protein Strain
Heading Accession and Version

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