Naa16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Naa16provided by RGD
Official Full Name: N(alpha)-acetyltransferase 16, NatA auxiliary subunitprovided by RGD
Primary source: RGD:1584324
See related: EnsemblRapid:ENSRNOG00000045863 AllianceGenome:RGD:1584324
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable acetyltransferase activator activity and ribosome binding activity. Predicted to be involved in N-terminal protein amino acid acetylation; negative regulation of apoptotic process; and protein stabilization. Predicted to be located in cytosol. Predicted to be part of NatA complex. Predicted to be active in cytoplasm. Orthologous to human NAA16 (N-alpha-acetyltransferase 16, NatA auxiliary subunit). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 109.4), Spleen (RPKM 89.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15q12

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (61120704..61179979, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (54711620..54770915, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (61597054..61655665, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH139849 (e-PCR)
- UniSTS:221933

RH127363 (e-PCR)
- UniSTS:210673

RH140846 (e-PCR)
- UniSTS:210673

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables acetyltransferase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables ribosome binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in N-terminal protein amino acid acetylation	IEA Inferred from Electronic Annotation more info
involved_in N-terminal protein amino acid acetylation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of NatA complex	IBA Inferred from Biological aspect of Ancestor more info
part_of NatA complex	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: N-alpha-acetyltransferase 16, NatA auxiliary subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001399534.1 → NP_001386463.1 N-alpha-acetyltransferase 16, NatA auxiliary subunit

Status: VALIDATED

Source sequence(s)

JAXUCZ010000015

UniProtKB/TrEMBL

A6HTY9, M0RC73

Related

ENSRNOP00000067183.3, ENSRNOT00000071805.4

Conserved Domains (4) summary

COG4783
Location:103 → 251

YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]

sd00006
Location:82 → 108

TPR; TPR repeat [structural motif]

pfam00515
Location:87 → 113

TPR_1; Tetratricopeptide repeat

pfam12569
Location:187 → 698

NARP1; NMDA receptor-regulated protein 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086033.1 Reference GRCr8

Range

61120704..61179979 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063274645.1 → XP_063130715.1 N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1
XM_039094047.2 → XP_038949975.1 N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1

Conserved Domains (4) summary

COG4783
Location:103 → 251

YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]

sd00006
Location:82 → 108

TPR; TPR repeat [structural motif]

pfam00515
Location:87 → 113

TPR_1; Tetratricopeptide repeat

pfam12569
Location:187 → 513

NARP1; NMDA receptor-regulated protein 1
XM_063274646.1 → XP_063130716.1 N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X2