Samm50 SAMM50 sorting and assembly machinery component [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Samm50provided by MGI
Official Full Name: SAMM50 sorting and assembly machinery componentprovided by MGI
Primary source: MGI:MGI:1915903
See related: Ensembl:ENSMUSG00000022437 AllianceGenome:MGI:1915903
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1110030L07Rik
Summary: Predicted to be involved in cristae formation; mitochondrial respiratory chain complex assembly; and protein insertion into mitochondrial outer membrane. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatotic liver disease. Orthologous to human SAMM50 (SAMM50 sorting and assembly machinery component). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Ubiquitous expression in heart adult (RPKM 17.2), kidney adult (RPKM 16.7) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 E2; 15 39.78 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (84076441..84100284)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (84192240..84216083)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cristae formation	ISO Inferred from Sequence Orthology more info
involved_in cristae formation	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial respiratory chain complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial respiratory chain complex assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein insertion into mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein insertion into mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
involved_in protein insertion into mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of SAM complex	IEA Inferred from Electronic Annotation more info
part_of SAM complex	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	HDA more info	PubMed
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: sorting and assembly machinery component 50 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.