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Tvp23b trans-golgi network vesicle protein 23 homolog B [ Rattus norvegicus (Norway rat) ]

Gene ID: 687358, updated on 28-Oct-2024

Summary

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Official Symbol
Tvp23bprovided by RGD
Official Full Name
trans-golgi network vesicle protein 23 homolog Bprovided by RGD
Primary source
RGD:1586539
See related
EnsemblRapid:ENSRNOG00000050649 AllianceGenome:RGD:1586539
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam18b2
Summary
Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be active in Golgi membrane. Orthologous to several human genes including TVP23B (trans-golgi network vesicle protein 23 homolog B). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Kidney (RPKM 301.4), Liver (RPKM 275.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tvp23b in Genome Data Viewer
Location:
10q23
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (48053005..48067326)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (47553789..47565203)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (49299125..49312814)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 16 Neighboring gene F-box and WD repeat domain containing 10 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC120095116 Neighboring gene uncharacterized LOC102552952

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC187848

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Golgi apparatus membrane protein TVP23 homolog B
Names
family with sequence similarity 18, member B2
trans-golgi network vesicle protein 23 B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107568.3 → NP_001101038.2  Golgi apparatus membrane protein TVP23 homolog B

    See identical proteins and their annotated locations for NP_001101038.2

    Status: VALIDATED

    Source sequence(s)
    BC168178, CK483802
    UniProtKB/TrEMBL
    A6HFC7, A6HFC9, M0R766
    Related
    ENSRNOP00000065284.1, ENSRNOT00000074853.3
    Conserved Domains (1) summary
    pfam05832
    Location:32 → 174
    DUF846; Eukaryotic protein of unknown function (DUF846)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    48053005..48067326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086835.2 → XP_038942763.1  Golgi apparatus membrane protein TVP23 homolog B isoform X1

    Conserved Domains (1) summary
    pfam05832
    Location:32 → 154
    DUF846; Eukaryotic protein of unknown function (DUF846)

  2. XM_017597529.3 → XP_017453018.1  Golgi apparatus membrane protein TVP23 homolog B isoform X2

RNA

  1. XR_010055246.1 RNA Sequence

  2. XR_010055248.1 RNA Sequence

  3. XR_010055245.1 RNA Sequence

  4. XR_010055249.1 RNA Sequence

  5. XR_010055250.1 RNA Sequence

  6. XR_010055247.1 RNA Sequence

  7. XR_010055252.1 RNA Sequence

  8. XR_010055251.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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