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Gucd1 guanylyl cyclase domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 687713, updated on 2-Nov-2024

Summary

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Official Symbol
Gucd1provided by RGD
Official Full Name
guanylyl cyclase domain containing 1provided by RGD
Primary source
RGD:1597571
See related
EnsemblRapid:ENSRNOG00000049952 AllianceGenome:RGD:1597571
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Involved in liver regeneration and response to cAMP. Orthologous to human GUCD1 (guanylyl cyclase domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 379.9), Kidney (RPKM 294.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gucd1 in Genome Data Viewer
Location:
20p12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (13145055..13155765)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (13145617..13156330)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (14096030..14102901)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene gamma-glutamyltransferase 1 Neighboring gene uncharacterized LOC120098976 Neighboring gene leucine rich repeat containing 75B Neighboring gene small nuclear ribonucleoprotein D3 polypeptide Neighboring gene uncharacterized LOC102556392 Neighboring gene microRNA 327 Neighboring gene uncharacterized LOC102556333

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. NEDD4 controls the expression of GUCD1, a protein upregulated in proliferating liver cells. Bellet MM, et al. Cell Cycle, 2014. PMID 24743017, Free PMC Article
  2. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC189376

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in liver regeneration IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to cAMP IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
protein GUCD1
Names
guanylyl cyclase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134997.3 → NP_001128469.2  protein GUCD1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    UniProtKB/TrEMBL
    B5DFC7

  2. NM_001412126.1 → NP_001399055.1  protein GUCD1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    13145055..13155765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099073.2 → XP_038955001.1  protein GUCD1 isoform X2

    UniProtKB/TrEMBL
    A6JKK5
    Conserved Domains (1) summary
    pfam09778
    Location:1 → 197
    Guanylate_cyc_2; Guanylylate cyclase

  2. XM_039099072.2 → XP_038955000.1  protein GUCD1 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ASP6
    Related
    ENSRNOP00000097309.1, ENSRNOT00000115916.2
    Conserved Domains (1) summary
    pfam09778
    Location:94 → 307
    Guanylate_cyc_2; Guanylylate cyclase
Nucleotide Protein Strain
Heading Accession and Version

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