Hbb-bs hemoglobin, beta adult s chain [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Hbb-bsprovided by RGD
Full Name: hemoglobin, beta adult s chainprovided by RGD
Primary source: RGD:1597422
See related: AllianceGenome:RGD:1597422
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in cellular oxidant detoxification and oxygen transport. Predicted to be part of hemoglobin complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Spleen (RPKM 101105.2), Lung (RPKM 20866.6) and 1 other tissue See more
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Genomic context

Location:: 1q32

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (167630245..167631630, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (158218356..158219741, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (168964202..168965568)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Hbb-b1 (e-PCR), detects polymorphism
- UniSTS:516684

Hbb-b1 (e-PCR), detects polymorphism
- UniSTS:531320

AI036344 (e-PCR)
- UniSTS:165546

Hbb-b1 (e-PCR), detects polymorphism
- UniSTS:499134

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxygen carrier activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbon dioxide transport	NAS Non-traceable Author Statement more info	PubMed
involved_in cellular oxidant detoxification	IEA Inferred from Electronic Annotation more info
involved_in nitric oxide transport	ISO Inferred from Sequence Orthology more info
involved_in oxygen transport	IEA Inferred from Electronic Annotation more info
involved_in oxygen transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of hemoglobin complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: hemoglobin subunit beta-2

Names: III beta-3 globin; beta-2-globin; beta-globin; beta-hemoglobin; hemoglobin beta chain, minor-form; hemoglobin beta-2 chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.