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Slc25a42 solute carrier family 25, member 42 [ Rattus norvegicus (Norway rat) ]

Gene ID: 689414, updated on 10-Jul-2024

Summary

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Official Symbol
Slc25a42provided by RGD
Official Full Name
solute carrier family 25, member 42provided by RGD
Primary source
RGD:1592346
See related
EnsemblRapid:ENSRNOG00000020345 AllianceGenome:RGD:1592346
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable adenine nucleotide transmembrane transporter activity and adenosine-diphosphatase activity. Predicted to be involved in adenine nucleotide transport. Predicted to be located in mitochondrion. Orthologous to human SLC25A42 (solute carrier family 25 member 42). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 119.2), Muscle (RPKM 88.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc25a42 in Genome Data Viewer
Location:
16p14
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19247874..19286598)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19213914..19251990)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (20962144..21000191)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene SURP and G patch domain containing 2 Neighboring gene U6 spliceosomal RNA Neighboring gene armadillo repeat containing 6 Neighboring gene transmembrane protein 161A Neighboring gene myocyte enhancer factor 2B Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene regulatory factor X-associated ankyrin-containing protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel member of solute carrier family 25 (SLC25A42) is a transporter of coenzyme A and adenosine 3',5'-diphosphate in human mitochondria. Fiermonte G, et al. J Biol Chem, 2009 Jul 3. PMID 19429682, Free PMC Article
  2. Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. Haitina T, et al. Genomics, 2006 Dec. PMID 16949250
  3. Proteomic analysis of the mouse liver mitochondrial inner membrane. Da Cruz S, et al. J Biol Chem, 2003 Oct 17. PMID 12865426
  4. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
  5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC188302

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ADP phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables ADP phosphatase activity ISO
Inferred from Sequence Orthology
more info
  
enables ADP phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ADP transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ADP transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables ADP transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables AMP transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables AMP transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables AMP transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ATP transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables ATP transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables coenzyme A transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables coenzyme A transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables coenzyme A transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in ADP transport IEA
Inferred from Electronic Annotation
more info
  
involved_in ADP transport ISO
Inferred from Sequence Orthology
more info
  
involved_in ADP transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in AMP transport IEA
Inferred from Electronic Annotation
more info
  
involved_in AMP transport ISO
Inferred from Sequence Orthology
more info
  
involved_in AMP transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in ATP transport IEA
Inferred from Electronic Annotation
more info
  
involved_in ATP transport ISO
Inferred from Sequence Orthology
more info
  
involved_in ATP transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in coenzyme A transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in coenzyme A transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in coenzyme A transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mitochondrial coenzyme A transporter SLC25A42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127590.1 → NP_001121062.1  mitochondrial coenzyme A transporter SLC25A42

    See identical proteins and their annotated locations for NP_001121062.1

    Status: PROVISIONAL

    Source sequence(s)
    BC160887
    UniProtKB/Swiss-Prot
    P0C546
    UniProtKB/TrEMBL
    B1H271
    Related
    ENSRNOP00000106072.1, ENSRNOT00000171044.1
    Conserved Domains (2) summary
    PTZ00169
    Location:34 → 295
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:29 → 122
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    19247874..19286598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063275745.1 → XP_063131815.1  mitochondrial coenzyme A transporter SLC25A42 isoform X2

  2. XM_063275744.1 → XP_063131814.1  mitochondrial coenzyme A transporter SLC25A42 isoform X1

    UniProtKB/TrEMBL
    A6KA79

  3. XM_063275746.1 → XP_063131816.1  mitochondrial coenzyme A transporter SLC25A42 isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C546.1 GenPept UniProtKB/Swiss-Prot:P0C546

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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