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Psmg4 proteasome assembly chaperone 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 689623, updated on 2-Nov-2024

Summary

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Official Symbol
Psmg4provided by RGD
Official Full Name
proteasome assembly chaperone 4provided by RGD
Primary source
RGD:1589955
See related
EnsemblRapid:ENSRNOG00000039265 AllianceGenome:RGD:1589955
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305541
Summary
Predicted to be involved in proteasome assembly. Predicted to be part of protein-containing complex. Orthologous to human PSMG4 (proteasome assembly chaperone 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 347.3), Kidney (RPKM 334.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Psmg4 in Genome Data Viewer
Location:
17p12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (30916031..30923430, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (30710682..30718035, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (31402581..31411924, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene PX domain containing 1 Neighboring gene solute carrier family 22, member 23 Neighboring gene uncharacterized LOC134482704 Neighboring gene uncharacterized LOC120097753 Neighboring gene uncharacterized LOC102551220

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. 20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals. Le Tallec B, et al. Mol Cell, 2007 Aug 17. PMID 17707236
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC189533

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in proteasome assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
proteasome assembly chaperone 4
Names
proteasome (prosome, macropain) assembly chaperone 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001129879.2 → NP_001123351.1  proteasome assembly chaperone 4

    See identical proteins and their annotated locations for NP_001123351.1

    Status: VALIDATED

    Source sequence(s)
    BC167096, BE113476, CN543825
    UniProtKB/TrEMBL
    B2RZB8
    Conserved Domains (1) summary
    pfam16093
    Location:28 → 95
    PAC4; Proteasome assembly chaperone 4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    30916031..30923430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096086.2 → XP_038952014.1  proteasome assembly chaperone 4 isoform X2

    UniProtKB/TrEMBL
    A6J7G2
    Related
    ENSRNOP00000099988.1, ENSRNOT00000128394.1
    Conserved Domains (1) summary
    pfam16093
    Location:28 → 69
    PAC4; Proteasome assembly chaperone 4

  2. XM_006253847.5 → XP_006253909.1  proteasome assembly chaperone 4 isoform X1

    Conserved Domains (1) summary
    pfam16093
    Location:28 → 83
    PAC4; Proteasome assembly chaperone 4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001109543.1: Suppressed sequence

    Description
    NM_001109543.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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