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Crygs crystallin, gamma S [ Rattus norvegicus (Norway rat) ]

Gene ID: 689897, updated on 2-Nov-2024

Summary

Official Symbol
Crygsprovided by RGD
Official Full Name
crystallin, gamma Sprovided by RGD
Primary source
RGD:1587483
See related
EnsemblRapid:ENSRNOG00000038355 AllianceGenome:RGD:1587483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Predicted to act upstream of or within morphogenesis of an epithelium. Human ortholog(s) of this gene implicated in cataract 20 multiple types. Orthologous to human CRYGS (crystallin gamma S). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Kidney (RPKM 3.0), Liver (RPKM 1.7) and 9 other tissues See more
Orthologs
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Genomic context

See Crygs in Genome Data Viewer
Location:
11q23
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (91711755..91716858)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (78207170..78212273)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (81796891..81802172)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member B11 Neighboring gene TBCC domain containing 1 Neighboring gene uncharacterized LOC100911962 Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
gamma-crystallin S
Names
beta-crystallin S
gamma-S-crystallin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109553.1NP_001103023.1  gamma-crystallin S

    See identical proteins and their annotated locations for NP_001103023.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473999
    UniProtKB/Swiss-Prot
    P0C5E9
    UniProtKB/TrEMBL
    A6JS55
    Related
    ENSRNOP00000055204.2, ENSRNOT00000058402.4
    Conserved Domains (1) summary
    pfam00030
    Location:786
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    91711755..91716858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270770.1XP_063126840.1  gamma-crystallin S isoform X1