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Unc80 unc-80 homolog, NALCN channel complex subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 689991, updated on 28-Oct-2024

Summary

Official Symbol
Unc80provided by RGD
Official Full Name
unc-80 homolog, NALCN channel complex subunitprovided by RGD
Primary source
RGD:1309976
See related
EnsemblRapid:ENSRNOG00000028362 AllianceGenome:RGD:1309976
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in plasma membrane. Predicted to be part of sodium channel complex. Orthologous to human UNC80 (unc-80 homolog, NALCN channel complex subunit). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Brain (RPKM 204.2) and Adrenal (RPKM 20.4) See more
Orthologs
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Genomic context

See Unc80 in Genome Data Viewer
Location:
9q32
Exon count:
65
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (75461618..75639849)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (68011940..68190135)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (73492907..73686578)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene splicing regulatory glutamic acid and lysine rich protein 1, pseudogene 1 Neighboring gene microtubule-associated protein 2 Neighboring gene KAT8 regulatory NSL complex subunit 1-like Neighboring gene ribulose-5-phosphate-3-epimerase Neighboring gene U7 small nuclear RNA Neighboring gene acyl-CoA dehydrogenase, long chain

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
protein unc-80 homolog
Names
unc-80 homolog, NALCN activator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    75461618..75639849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084598.2XP_038940526.1  protein unc-80 homolog isoform X1

    Conserved Domains (1) summary
    pfam15778
    Location:16236
    UNC80; Cation channel complex component UNC80
  2. XM_063268134.1XP_063124204.1  protein unc-80 homolog isoform X8

  3. XM_063268135.1XP_063124205.1  protein unc-80 homolog isoform X9

  4. XM_063268136.1XP_063124206.1  protein unc-80 homolog isoform X10

    Related
    ENSRNOP00000104902.1, ENSRNOT00000142637.1
  5. XM_063268130.1XP_063124200.1  protein unc-80 homolog isoform X2

  6. XM_063268137.1XP_063124207.1  protein unc-80 homolog isoform X11

  7. XM_063268133.1XP_063124203.1  protein unc-80 homolog isoform X5

  8. XM_039084601.2XP_038940529.1  protein unc-80 homolog isoform X12

    Related
    ENSRNOP00000068926.3, ENSRNOT00000089478.3
    Conserved Domains (1) summary
    pfam15778
    Location:16236
    UNC80; Cation channel complex component UNC80
  9. XM_063268138.1XP_063124208.1  protein unc-80 homolog isoform X13

  10. XM_063268131.1XP_063124201.1  protein unc-80 homolog isoform X3

  11. XM_039084599.2XP_038940527.1  protein unc-80 homolog isoform X6

    Conserved Domains (1) summary
    pfam15778
    Location:16236
    UNC80; Cation channel complex component UNC80
  12. XM_039084600.2XP_038940528.1  protein unc-80 homolog isoform X7

    UniProtKB/TrEMBL
    D3ZXX3
    Related
    ENSRNOP00000035988.5, ENSRNOT00000032430.6
    Conserved Domains (1) summary
    pfam15778
    Location:16236
    UNC80; Cation channel complex component UNC80
  13. XM_063268139.1XP_063124209.1  protein unc-80 homolog isoform X14

  14. XM_063268140.1XP_063124210.1  protein unc-80 homolog isoform X15

    UniProtKB/TrEMBL
    A0A0G2JU17
  15. XM_063268132.1XP_063124202.1  protein unc-80 homolog isoform X4

  16. XM_039084602.2XP_038940530.1  protein unc-80 homolog isoform X17

    Conserved Domains (1) summary
    pfam15778
    Location:16236
    UNC80; Cation channel complex component UNC80
  17. XM_063268141.1XP_063124211.1  protein unc-80 homolog isoform X16