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Klra4 killer cell lectin-like receptor, subfamily A, member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690020, updated on 10-Jul-2024

Summary

Official Symbol
Klra4provided by RGD
Official Full Name
killer cell lectin-like receptor, subfamily A, member 4provided by RGD
Primary source
RGD:1585190
See related
EnsemblRapid:ENSRNOG00000053656 AllianceGenome:RGD:1585190
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 4.6), Thymus (RPKM 3.9) and 5 other tissues See more
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Genomic context

See Klra4 in Genome Data Viewer
Location:
4q42
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (165005146..165026189, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (163319139..163340140, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (163628633..163649820, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor family I member 2 Neighboring gene killer cell lectin-like receptor subfamily H, member 1 Neighboring gene killer cell lectin-like receptor, subfamily A, member 5, pseudogene 3 Neighboring gene killer cell lectin-like receptor, subfamily A, member 17

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
killer cell lectin-like receptor 2; killer cell lectin-like receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    165005146..165026189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108856.2XP_038964784.1  killer cell lectin-like receptor 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6GFJ6
    Conserved Domains (1) summary
    pfam08391
    Location:86187
    Ly49; Ly49-like protein, N-terminal region
  2. XM_006237109.5XP_006237171.1  killer cell lectin-like receptor 2 isoform X4

    See identical proteins and their annotated locations for XP_006237171.1

    Related
    ENSRNOP00000072534.2, ENSRNOT00000080873.3
    Conserved Domains (2) summary
    cd03593
    Location:194269
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    pfam08391
    Location:86205
    Ly49; Ly49-like protein, N-terminal region
  3. XM_063286986.1XP_063143056.1  killer cell lectin-like receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K381
  4. XM_039108855.2XP_038964783.1  killer cell lectin-like receptor 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6GFJ6
    Conserved Domains (1) summary
    pfam08391
    Location:86187
    Ly49; Ly49-like protein, N-terminal region
  5. XM_039108857.2XP_038964785.1  killer cell lectin-like receptor 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6GFJ6
    Conserved Domains (1) summary
    pfam08391
    Location:86187
    Ly49; Ly49-like protein, N-terminal region
  6. XM_039108859.2XP_038964787.1  killer cell lectin-like receptor 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6GFJ6
    Conserved Domains (1) summary
    pfam08391
    Location:86187
    Ly49; Ly49-like protein, N-terminal region
  7. XM_039108854.2XP_038964782.1  killer cell lectin-like receptor 4 isoform X3

    Conserved Domains (2) summary
    cd03593
    Location:194269
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    pfam08391
    Location:86205
    Ly49; Ly49-like protein, N-terminal region
  8. XM_039108858.2XP_038964786.1  killer cell lectin-like receptor 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6GFJ6
    Conserved Domains (1) summary
    pfam08391
    Location:86187
    Ly49; Ly49-like protein, N-terminal region
  9. XM_039108852.2XP_038964780.1  killer cell lectin-like receptor 4 isoform X2

    Conserved Domains (2) summary
    cd03593
    Location:194285
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    pfam08391
    Location:86205
    Ly49; Ly49-like protein, N-terminal region

RNA

  1. XR_005504002.2 RNA Sequence