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Harbi1 harbinger transposase derived 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690164, updated on 2-Nov-2024

Summary

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Official Symbol
Harbi1provided by RGD
Official Full Name
harbinger transposase derived 1provided by RGD
Primary source
RGD:1584007
See related
EnsemblRapid:ENSRNOG00000081861 AllianceGenome:RGD:1584007
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable metal ion binding activity and nuclease activity. Predicted to be located in centriolar satellite; cytosol; and plasma membrane. Orthologous to human HARBI1 (harbinger transposase derived 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 21.5), Kidney (RPKM 19.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Harbi1 in Genome Data Viewer
Location:
3q24
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (98137087..98145992)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (77681431..77689749)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (80614886..80624213)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 408 Neighboring gene Rho GTPase activating protein 1 Neighboring gene autophagy related 13 Neighboring gene autophagy and beclin 1 regulator 1 Neighboring gene uncharacterized LOC134486121 Neighboring gene cholinergic receptor, muscarinic 4 Neighboring gene midkine

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
putative nuclease HARBI1
Names
Harbinger transposase-derived nuclease
NP_001107265.2
XP_063140650.1
XP_063140651.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113793.3 → NP_001107265.2  putative nuclease HARBI1

    See identical proteins and their annotated locations for NP_001107265.2

    Status: VALIDATED

    Source sequence(s)
    BC158734
    UniProtKB/Swiss-Prot
    B0BN95
    Conserved Domains (1) summary
    pfam13359
    Location:148 → 300
    DDE_Tnp_4; DDE superfamily endonuclease

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    98137087..98145992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284581.1 → XP_063140651.1  putative nuclease HARBI1 isoform X1

    Related
    ENSRNOP00000108066.1, ENSRNOT00000132207.1

  2. XM_063284580.1 → XP_063140650.1  putative nuclease HARBI1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B0BN95.1 GenPept UniProtKB/Swiss-Prot:B0BN95

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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