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Btbd6 BTB domain containing 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690367, updated on 2-Nov-2024

Summary

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Official Symbol
Btbd6provided by RGD
Official Full Name
BTB domain containing 6provided by RGD
Primary source
RGD:1597323
See related
EnsemblRapid:ENSRNOG00000014693 AllianceGenome:RGD:1597323
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in neurogenesis. Predicted to be active in cytosol. Orthologous to human BTBD6 (BTB domain containing 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 119.9), Adrenal (RPKM 109.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Btbd6 in Genome Data Viewer
Location:
6q32
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (137879202..137881662)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (132058094..132060603)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137785662..137788442)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene jagged canonical Notch ligand 2 Neighboring gene nudix hydrolase 14 Neighboring gene BRF1, RNA polymerase III transcription initiation factor subunit Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC134479482 Neighboring gene uncharacterized LOC134479483

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis. Ahmed F, et al. Invest Ophthalmol Vis Sci, 2004 Sep. PMID 15326124
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC156832

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein 6
Names
BTB (POZ) domain containing 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077683.2 → NP_001071151.2  BTB/POZ domain-containing protein 6

    Status: VALIDATED

    Source sequence(s)
    BC127548, BM386388, DV213761
    UniProtKB/TrEMBL
    A0A8I5ZW64, A6KBX4, F1M7U0
    Related
    ENSRNOP00000019768.5, ENSRNOT00000019768.7
    Conserved Domains (4) summary
    smart00225
    Location:138 → 237
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:243 → 349
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:130 → 233
    BTB; BTB/POZ domain
    pfam08005
    Location:394 → 537
    PHR; PHR domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    137879202..137881662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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