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Rbis ribosomal biogenesis factor [ Mus musculus (house mouse) ]

Gene ID: 69126, updated on 2-Nov-2024

Summary

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Official Symbol
Rbisprovided by MGI
Official Full Name
ribosomal biogenesis factorprovided by MGI
Primary source
MGI:MGI:1916376
See related
Ensembl:ENSMUSG00000078784 AllianceGenome:MGI:1916376
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810022K09Rik
Summary
Predicted to be involved in ribosome biogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleolus. Orthologous to human RBIS (ribosomal biogenesis factor). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E14 (RPKM 23.0), CNS E11.5 (RPKM 20.0) and 18 other tissues See more
Orthologs
human all
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Genomic context

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See Rbis in Genome Data Viewer
Location:
3 A1; 3 3.11 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (14671349..14676419, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (14606289..14611256, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene leucine rich repeat and coiled-coil domain containing 1 Neighboring gene E2F transcription factor 5 Neighboring gene STARR-positive B cell enhancer ABC_E2065 Neighboring gene STARR-seq mESC enhancer starr_07000 Neighboring gene STARR-seq mESC enhancer starr_07001 Neighboring gene predicted gene, 54191 Neighboring gene STARR-seq mESC enhancer starr_07003 Neighboring gene carbonic anhydrase 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Systems genetic analysis of hippocampal neuroanatomy and spatial learning in mice. Delprato A, et al. Genes Brain Behav, 2015 Nov. PMID 26449520, Free PMC Article
  2. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome biogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosome biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ribosomal biogenesis factor
Names
uncharacterized protein C8orf59 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099674.1 → NP_001093144.1  ribosomal biogenesis factor isoform 2

    See identical proteins and their annotated locations for NP_001093144.1

    Status: VALIDATED

    Source sequence(s)
    AK007585, BC055766, BC100487
    Consensus CDS
    CCDS79886.1
    UniProtKB/Swiss-Prot
    G3UW58, Q0VG62
    Related
    ENSMUSP00000139512.2, ENSMUST00000185384.7
    Conserved Domains (1) summary
    pfam15679
    Location:1 → 97
    DUF4665; Domain of unknown function (DUF4665)

  2. NM_001347206.1 → NP_001334135.1  ribosomal biogenesis factor isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC140350, BC115807
    Consensus CDS
    CCDS84610.1
    UniProtKB/Swiss-Prot
    Q0VG62
    Related
    ENSMUSP00000104002.3, ENSMUST00000108365.4
    Conserved Domains (1) summary
    pfam15679
    Location:43 → 139
    DUF4665; Domain of unknown function (DUF4665)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    14671349..14676419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319707.3 → XP_017175196.1  ribosomal biogenesis factor isoform X1

    Conserved Domains (1) summary
    pfam15679
    Location:43 → 119
    DUF4665; Domain of unknown function (DUF4665)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VG62.2 GenPept UniProtKB/Swiss-Prot:Q0VG62

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