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Katnbl1 katanin regulatory subunit B1 like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691543, updated on 2-Nov-2024

Summary

Symbol
Katnbl1provided by RGD
Full Name
katanin regulatory subunit B1 like 1provided by RGD
Primary source
RGD:1582771
See related
EnsemblRapid:ENSRNOG00000005814 AllianceGenome:RGD:1582771
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in cytoplasmic microtubule organization and positive regulation of cytoskeleton organization. Predicted to be located in several cellular components, including cleavage furrow; midbody; and mitotic spindle pole. Predicted to be part of katanin complex. Predicted to be active in nucleolus. Orthologous to human KATNBL1 (katanin regulatory subunit B1 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 108.7), Lung (RPKM 76.8) and 9 other tissues See more
Orthologs
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Genomic context

See Katnbl1 in Genome Data Viewer
Location:
3q35
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (119638068..119680179)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (99183748..99225789)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (103511653..103513498)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 12, member 6 Neighboring gene NOP10 ribonucleoprotein Neighboring gene 60S ribosomal protein L19-like Neighboring gene ER membrane protein complex subunit 4 Neighboring gene ER membrane protein complex subunit 7 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene cholinergic receptor, muscarinic 5 Neighboring gene apoptosis and caspase activation inhibitor

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic microtubule organization ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cleavage furrow IEA
Inferred from Electronic Annotation
more info
 
located_in cleavage furrow ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of katanin complex ISO
Inferred from Sequence Orthology
more info
 
located_in midbody IEA
Inferred from Electronic Annotation
more info
 
located_in midbody ISO
Inferred from Sequence Orthology
more info
 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
 
located_in mitotic spindle pole ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
KATNB1-like protein 1
Names
katanin p80 subunit B-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109645.2NP_001103115.1  KATNB1-like protein 1

    See identical proteins and their annotated locations for NP_001103115.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161951
    UniProtKB/TrEMBL
    A0A8I6A3S7, B1WBZ9, F7FMD9
    Related
    ENSRNOP00000007688.3, ENSRNOT00000007688.7
    Conserved Domains (1) summary
    pfam13925
    Location:148291
    Katanin_con80; con80 domain of Katanin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    119638068..119680179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284595.1XP_063140665.1  KATNB1-like protein 1 isoform X1

    Related
    ENSRNOP00000104286.1, ENSRNOT00000145699.1