Terb2 telomere repeat binding bouquet formation protein 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Terb2provided by RGD
Official Full Name: telomere repeat binding bouquet formation protein 2provided by RGD
Primary source: RGD:1593334
See related: EnsemblRapid:ENSRNOG00000037178 AllianceGenome:RGD:1593334
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Predicted to act upstream of or within meiosis I; oogenesis; and spermatogenesis. Predicted to be located in chromosome, telomeric region and nuclear envelope. Predicted to be active in nuclear inner membrane. Human ortholog(s) of this gene implicated in spermatogenic failure 59. Orthologous to human TERB2 (telomere repeat binding bouquet formation protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 6.2), Thymus (RPKM 5.5) and 1 other tissue See more
Orthologs: human mouse all
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Genomic context

Location:: 3q35

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (129591933..129610293)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (109138343..109156700)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (114129387..114147943)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within double-strand break repair involved in meiotic recombination	ISO Inferred from Sequence Orthology more info
involved_in homologous chromosome pairing at meiosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within homologous chromosome pairing at meiosis	ISO Inferred from Sequence Orthology more info
involved_in homologous chromosome pairing at meiosis	ISO Inferred from Sequence Orthology more info
involved_in meiotic attachment of telomere to nuclear envelope	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within meiotic attachment of telomere to nuclear envelope	ISO Inferred from Sequence Orthology more info
involved_in meiotic attachment of telomere to nuclear envelope	ISO Inferred from Sequence Orthology more info
involved_in meiotic telomere clustering	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within oogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within spermatogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within synaptonemal complex assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
located_in nuclear envelope	ISO Inferred from Sequence Orthology more info
is_active_in nuclear inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear inner membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: telomere repeats-binding bouquet formation protein 2

Names: uncharacterized protein C15orf43 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.