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Zfp688 zinc finger protein 688 [ Mus musculus (house mouse) ]

Gene ID: 69234, updated on 28-Oct-2024

Summary

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Official Symbol
Zfp688provided by MGI
Official Full Name
zinc finger protein 688provided by MGI
Primary source
MGI:MGI:1916484
See related
Ensembl:ENSMUSG00000045251 AllianceGenome:MGI:1916484
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810407K09Rik
Summary
Is expressed in several structures, including brain; genitourinary system; and retina nuclear layer. Orthologous to human ZNF688 (zinc finger protein 688). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in testis adult (RPKM 4.7), spleen adult (RPKM 4.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp688 in Genome Data Viewer
Location:
7 F3; 7 69.51 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127018138..127023786, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127418963..127423241, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 764 Neighboring gene SMT3 suppressor of mif two 3 homolog 2, pseudogene 2 (S. cerevisiae) Neighboring gene myeloma-overexpressed gene 2 protein homolog Neighboring gene STARR-seq mESC enhancer starr_20181 Neighboring gene RIKEN cDNA B130055M24 gene Neighboring gene STARR-positive B cell enhancer ABC_E1095 Neighboring gene zinc finger protein 689 Neighboring gene STARR-seq mESC enhancer starr_20182 Neighboring gene STARR-seq mESC enhancer starr_20183 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134614302-134614485 Neighboring gene STARR-positive B cell enhancer ABC_E1742 Neighboring gene proline rich 14 Neighboring gene fibrosin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
  2. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
  3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
  4. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
  5. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC41678

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
zinc finger protein 688

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026999.4 → NP_081275.3  zinc finger protein 688

    Status: VALIDATED

    Source sequence(s)
    AI447502, BC038680, BQ550868, DV654233
    Consensus CDS
    CCDS21866.2
    UniProtKB/TrEMBL
    E9Q5M9
    Related
    ENSMUSP00000101907.2, ENSMUST00000106300.2
    Conserved Domains (6) summary
    smart00349
    Location:26 → 86
    KRAB; krueppel associated box
    COG5048
    Location:166 → 233
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:183 → 203
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:181 → 203
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:26 → 65
    KRAB; KRAB box
    pfam13465
    Location:196 → 220
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    127018138..127023786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508179.5 → XP_006508242.1  zinc finger protein 688 isoform X1

    Conserved Domains (4) summary
    sd00017
    Location:145 → 165
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:143 → 165
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:25 → 66
    KRAB; KRAB box
    pfam13465
    Location:158 → 182
    zf-H2C2_2; Zinc-finger double domain

  2. XM_017312285.3 → XP_017167774.1  zinc finger protein 688 isoform X2

    UniProtKB/TrEMBL
    Q8K184
    Conserved Domains (3) summary
    sd00017
    Location:106 → 126
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:104 → 126
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:119 → 143
    zf-H2C2_2; Zinc-finger double domain

  3. XM_011241892.4 → XP_011240194.1  zinc finger protein 688 isoform X2

    UniProtKB/TrEMBL
    Q8K184
    Conserved Domains (3) summary
    sd00017
    Location:106 → 126
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:104 → 126
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:119 → 143
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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