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Fib-l silk fibroin light chain [ Bombyx mori (domestic silkworm) ]

Gene ID: 693047, updated on 9-Feb-2024

Summary

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Gene symbol
Fib-l
Gene description
silk fibroin light chain
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bombyx mori
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx
Also known as
FIBL; Fib-1; fibroin
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Genomic context

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See Fib-l in Genome Data Viewer
Location:
chromosome: 14
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_01 current ASM3026992v2 (GCF_030269925.1) 14 NC_085120.1 (9684953..9698235, complement)
103 previous assembly Bmori_2016v1.0 (GCF_014905235.1) 14 NC_051371.1 (9685264..9698548, complement)

Chromosome 14 - NC_085120.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105841523 Neighboring gene uncharacterized LOC101743535 Neighboring gene uncharacterized LOC105841524 Neighboring gene uncharacterized LOC134200124

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo. Chen Y, et al. J Cell Biochem, 2019 Sep. PMID 31106458
  2. Production of a chimeric fibroin light-chain polypeptide in a fibroin secretion-deficient naked pupa mutant of the silkworm Bombyx mori. Mori K, et al. J Mol Biol, 1995 Aug 11. PMID 7643398
  3. Primary structure of the silk fibroin light chain determined by cDNA sequencing and peptide analysis. Yamaguchi K, et al. J Mol Biol, 1989 Nov 5. PMID 2585514
  4. Structure of the Bombyx mori fibroin light-chain-encoding gene: upstream sequence elements common to the light and heavy chain. Kikuchi Y, et al. Gene, 1992 Jan 15. PMID 1347033
  5. Time-resolved structural investigation of regenerated silk fibroin nanofibers treated with solvent vapor. Jeong L, et al. Int J Biol Macromol, 2006 Mar 30. PMID 16545448

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo.
    Title: Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo.
  2. At least 4 microRNAs target fibroin L chain transcripts, suggesting that miRNAs might play an important role in the regulation of silk protein production.
    Title: Identification of conserved microRNAs in Bombyx mori (silkworm) and regulation of fibroin L chain production by microRNAs in heterologous system.
  3. Structural changes of solvent-vapor-treated SF nanofibers were studied using time-resolved IR spectroscopy. Conformational transitions from random coils to beta-sheets depended on the solvent vapor used. Treatment temperatures affected transition rates.
    Title: Time-resolved structural investigation of regenerated silk fibroin nanofibers treated with solvent vapor.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroin light chain
Names
L-fibroin
fibroin L-chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044023.1 → NP_001037488.1  fibroin light chain precursor

    See identical proteins and their annotated locations for NP_001037488.1

    Status: PROVISIONAL

    Source sequence(s)
    M76430
    UniProtKB/Swiss-Prot
    P21828, Q17224
    UniProtKB/TrEMBL
    A0A8R1XET8
    Conserved Domains (1) summary
    pfam05849
    Location:18 → 256
    L-fibroin; Fibroin light chain (L-fibroin)

RefSeqs of Annotated Genomes: GCF_030269925.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM3026992v2 Primary Assembly

Genomic

  1. NC_085120.1 Reference ASM3026992v2 Primary Assembly

    Range
    9684953..9698235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P21828.1 GenPept UniProtKB/Swiss-Prot:P21828

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials