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bvgA virulence factors two-component system response regulator BvgA [ Bordetella pertussis ]

Gene ID: 69601662, updated on 1-Aug-2024

Summary

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Gene symbol
bvgA
Gene description
virulence factors two-component system response regulator BvgA
Locus tag
CXD86_RS09090
Gene type
protein coding
RefSeq status
PIPELINE
Organism
Bordetella pertussis (strain: H640, nat-host: Homo sapiens)
Lineage
Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella
Old locus tag
CXD86_09045
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Genomic context

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NZ_CP025371.1Genomic Context describing neighboring genes Neighboring gene EAL domain-containing protein Neighboring gene virulence factors two-component system sensor histidine kinase BvgS Neighboring gene filamentous hemagglutinin/adhesin Neighboring gene protein FimA

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP025371.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bordetella pertussis fim3 gene regulation by BvgA: phosphorylation controls the formation of inactive vs. active transcription complexes. Boulanger A, et al. Proc Natl Acad Sci U S A, 2015 Feb 10. PMID 25624471, Free PMC Article
  2. In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA. Boulanger A, et al. Mol Microbiol, 2013 Apr. PMID 23489959, Free PMC Article
  3. Dimerization of signalling modules of the EvgAS and BvgAS phosphorelay systems. Perraud AL, et al. Biochim Biophys Acta, 2000 May 23. PMID 10825546
  4. Autophosphorylation and phosphotransfer in the Bordetella pertussis BvgAS signal transduction cascade. Uhl MA, et al. Proc Natl Acad Sci U S A, 1994 Feb 1. PMID 8302847, Free PMC Article
  5. Genomic Survey of Bordetella pertussis Diversity, United States, 2000-2013. Weigand MR, et al. Emerg Infect Dis, 2019 Apr. PMID 30882317, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
virulence factors two-component system response regulator BvgA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP025371.1 Reference assembly

    Range
    1853371..1854000 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010930609.1 MULTISPECIES: virulence factors two-component system response regulator BvgA [Bordetella]

    See identical proteins and their annotated locations for WP_010930609.1

    Status: PIPELINE

    UniProtKB/Swiss-Prot
    P0A4H2, P0A4H3, P0A4H4, P16574
    UniProtKB/TrEMBL
    A0A0E8BMW2, A0A0T7CP47, A0A291KZA7, A0AAI9IZD6
    Conserved Domains (1) summary
    COG2197
    Location:4 → 208
    CitB; DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0A4H2.1