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Ms4a10 membrane-spanning 4-domains, subfamily A, member 10 [ Mus musculus (house mouse) ]

Gene ID: 69826, updated on 2-Nov-2024

Summary

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Official Symbol
Ms4a10provided by MGI
Official Full Name
membrane-spanning 4-domains, subfamily A, member 10provided by MGI
Primary source
MGI:MGI:1917076
See related
Ensembl:ENSMUSG00000024731 AllianceGenome:MGI:1917076
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010001N17Rik
Summary
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human MS4A10 (membrane spanning 4-domains A10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in duodenum adult (RPKM 138.7), small intestine adult (RPKM 67.1) and 1 other tissue See more
Orthologs
human all
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Genomic context

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See Ms4a10 in Genome Data Viewer
Location:
19 A; 19 7.44 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10939653..10952088, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10962289..10974724, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene zona pellucida glycoprotein 1 Neighboring gene prostaglandin D2 receptor 2 Neighboring gene STARR-positive B cell enhancer ABC_E5689 Neighboring gene coiled-coil domain containing 86 Neighboring gene STARR-seq mESC enhancer starr_45563 Neighboring gene STARR-positive B cell enhancer ABC_E11021 Neighboring gene STARR-positive B cell enhancer mm9_chr19:11054242-11054543 Neighboring gene membrane-spanning 4-domains, subfamily A, member 15 Neighboring gene membrane-spanning 4-domains, subfamily A, member 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor. Ishibashi K, et al. Gene, 2001 Feb 7. PMID 11245982
  2. Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. Liang Y, et al. Genomics, 2001 Mar 1. PMID 11401424
  3. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
membrane-spanning 4-domains subfamily A member 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001379527.1 → NP_001366456.1  membrane-spanning 4-domains subfamily A member 10 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC148991
    UniProtKB/TrEMBL
    B7ZN09
    Conserved Domains (1) summary
    pfam04103
    Location:57 → 187
    CD20; CD20-like family

  2. NM_023529.3 → NP_076018.2  membrane-spanning 4-domains subfamily A member 10 isoform 1

    See identical proteins and their annotated locations for NP_076018.2

    Status: VALIDATED

    Source sequence(s)
    AC148991, AF237918
    Consensus CDS
    CCDS37919.1
    UniProtKB/Swiss-Prot
    Q99N03, Q9D8H8, Q9EQY8
    UniProtKB/TrEMBL
    B2RWS0, B7ZN09
    Related
    ENSMUSP00000072531.7, ENSMUST00000072748.13
    Conserved Domains (1) summary
    pfam04103
    Location:57 → 187
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    10939653..10952088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527329.3 → XP_006527392.1  membrane-spanning 4-domains subfamily A member 10 isoform X1

    See identical proteins and their annotated locations for XP_006527392.1

    UniProtKB/TrEMBL
    B7ZN09
    Related
    ENSMUSP00000140111.2, ENSMUST00000191343.7

  2. XM_011247338.2 → XP_011245640.1  membrane-spanning 4-domains subfamily A member 10 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99N03.1 GenPept UniProtKB/Swiss-Prot:Q99N03

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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