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Fam162a family with sequence similarity 162, member A [ Mus musculus (house mouse) ]

Gene ID: 70186, updated on 2-Nov-2024

Summary

Official Symbol
Fam162aprovided by MGI
Official Full Name
family with sequence similarity 162, member Aprovided by MGI
Primary source
MGI:MGI:1917436
See related
Ensembl:ENSMUSG00000003955 AllianceGenome:MGI:1917436
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HGTD-P; 2310056P07Rik
Summary
Involved in several processes, including cellular response to hypoxia; neuron apoptotic process; and positive regulation of release of cytochrome c from mitochondria. Located in mitochondrion. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human FAM162A (family with sequence similarity 162 member A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in bladder adult (RPKM 58.3), limb E14.5 (RPKM 45.7) and 26 other tissues See more
Orthologs
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Genomic context

See Fam162a in Genome Data Viewer
Location:
16 B3; 16 25.43 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (35864214..35891931, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (36043844..36071561, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene karyopherin subunit alpha 1 Neighboring gene STARR-positive B cell enhancer ABC_E5540 Neighboring gene WD repeat domain 5B Neighboring gene STARR-seq mESC enhancer starr_40755 Neighboring gene mitochondrial matrix import factor 23 Neighboring gene STARR-seq mESC enhancer starr_40756 Neighboring gene STARR-seq mESC enhancer starr_40757 Neighboring gene predicted gene, 41450

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to hypoxia IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cellular response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of release of cytochrome c from mitochondria IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of release of cytochrome c from mitochondria IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of release of cytochrome c from mitochondria ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein FAM162A
Names
E2-induced gene 5 protein homolog
growth and transformation-dependent protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027342.2NP_081618.1  protein FAM162A

    See identical proteins and their annotated locations for NP_081618.1

    Status: VALIDATED

    Source sequence(s)
    CT573031
    Consensus CDS
    CCDS28146.1
    UniProtKB/Swiss-Prot
    Q9D6U8
    Related
    ENSMUSP00000004057.8, ENSMUST00000004057.9
    Conserved Domains (1) summary
    pfam06388
    Location:28153
    DUF1075; Protein of unknown function (DUF1075)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    35864214..35891931 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)