Arpin actin-related protein 2/3 complex inhibitor [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Arpinprovided by MGI
Official Full Name: actin-related protein 2/3 complex inhibitorprovided by MGI
Primary source: MGI:MGI:1917670
See related: Ensembl:ENSMUSG00000039043 AllianceGenome:MGI:1917670
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2610034B18Rik
Summary: Predicted to be involved in directional locomotion; negative regulation of cell migration; and negative regulation of cellular component organization. Located in lamellipodium. Orthologous to several human genes including ARPIN (actin related protein 2/3 complex inhibitor). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in large intestine adult (RPKM 19.4), small intestine adult (RPKM 10.1) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 45.27 cM; 7 D2

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (79575107..79585012, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (79925359..79935264, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in directional locomotion	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of actin nucleation	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of actin nucleation	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of cell migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of lamellipodium morphogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in lamellipodium	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: arpin

Names: UPF0552 protein C15orf38 homolog; arp2/3 inhibition protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.